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Clinical Journal of Gastroenterology

, Volume 11, Issue 4, pp 333–337 | Cite as

Neuroendocrine neoplasm of pancreas with cystic degeneration mimicking mucinous cystic neoplasm

  • Uayporn Kaosombatwattana
  • Yoshiki Hirooka
  • Hiroki Kawashima
  • Eizaburo Ohno
  • Takuya Ishikawa
  • Hiroki Suhara
  • Hidemi Goto
Case Report
  • 115 Downloads

Abstract

Endoscopic ultrasound is increasingly being used for evaluation of pancreatic diseases and pancreatic tumors. Among various pancreatic cystic lesions, cystic degeneration of pancreatic neuroendocrine neoplasm is of the challenge in making diagnosis. Although unique characteristic of each type of pancreatic cystic lesions has been proposed abundantly, typical morphology of cystic degeneration of pancreatic neuroendocrine neoplasm is still unclear. We, herein, reported a case of 66-year-old woman who was incidentally found to have a cystic lesion in the tail of pancreas upon screening transabdominal ultrasonography. A well-defined cystic lesion with rim calcification was noted on subsequent abdominal computed tomography. Endoscopic ultrasound revealed a markedly thick-wall cystic lesion containing solid nodule inside which was not enhanced following contrast-enhanced study. A mucinous cystic neoplasm was suspected and the patient was proceeded with distal pancreatectomy. A definite diagnosis of neuroendocrine neoplasm was confirmed after staining with synaptophysin and chromogranin A. We performed a meticulous review on current literatures focusing on endoscopic characteristics of pancreatic neuroendocrine neoplasms with cystic degeneration.

Keywords

Pancreatic neuroendocrine neoplasm Cystic degeneration Pancreatic cystic lesion Endoscopic ultrasound Rim calcification 

Notes

Acknowledgements

The authors declare that they have no competing interests and no funding was received for this case report.

Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

Human rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

Informed consent was obtained from the patient for being included in the report.

Supplementary material

12328_2018_846_MOESM1_ESM.mp4 (1.4 mb)
Supplementary material 1 VDO: Contrast-enhanced EUS first minute after injection with Sonazoid (MP4 1470 kb)

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Copyright information

© Japanese Society of Gastroenterology 2018

Authors and Affiliations

  1. 1.Department of Gastroenterology and HepatologyNagoya University Graduate School of MedicineAichiJapan
  2. 2.Department of EndoscopyNagoya University HospitalNagoyaJapan
  3. 3.Department of Medicine, Faculty of Medicine Siriraj HospitalMahidol UniversityBangkokThailand

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