Clinical Journal of Gastroenterology

, Volume 11, Issue 3, pp 224–228 | Cite as

Gastrointestinal histoplasmosis ileal stricture successfully treated with through-the-scope balloon dilation in a patient with hyperimmunoglobulin M syndrome

  • Fredy Nehme
  • Kyle Rowe
  • Mohamad El Hawari
  • Maha Assi
  • Imad Nassif
Case Report


Gastrointestinal histoplasmosis is common in patients with disseminated disease affecting both immunocompetent and immunocompromised patients. However, it is often unrecognized due to a lack of specific signs and symptoms. It has only rarely been reported to cause small bowel obstruction, during which surgical treatment was nearly always necessary. Little is known about the usefulness of endoscopic therapy in gastrointestinal histoplasmosis associated strictures. We report the case of a 32-year-old man with a history of hyperimmunoglobulin M syndrome who presented with small bowel obstruction secondary to disseminated gastrointestinal histoplasmosis. Treatment was successful with a through-the-scope balloon dilator in combination with medical therapy. This report adds to the limited data available on the benefit of endoscopic therapy in infectious strictures, particularly gastrointestinal histoplasmosis.


Gastrointestinal histoplasmosis Ileal stricture Hyperimmunoglobulin M syndrome 


Compliance with ethical standards

Conflict of Interest

Fredy Nehme, Kyle Rowe, Mohamad El Hawari, Maha Assi and Imad Nassif declare that they have no conflict of interest

Human/animal Rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed Consent

Informed consent was obtained from all patients for being included in the study.


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Copyright information

© Japanese Society of Gastroenterology 2018

Authors and Affiliations

  1. 1.Department of Internal MedicineKansas University School of Medicine-WichitaWichitaUSA
  2. 2.Department of RadiologyKansas University School of Medicine-WichitaWichitaUSA

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