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Periappendicitis during adalimumab treatment for ileocecal Crohn’s disease in a 29-year-old male

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Abstract

A 29-year-old male was diagnosed with ileocolic Crohn’s disease (CD) approximately 2 years ago. Adalimumab was prescribed as CD remission induction therapy. Three months after beginning adalimumab, watery diarrhea and lower abdominal pain developed. He was admitted under a diagnosis of CD exacerbation. Despite fasting and antibiotic treatment, symptoms of acute panperitonitis appeared. He was diagnosed as acute appendicitis and we performed emergency surgery for peritoneal drainage and ileocecal resection on the fifth hospital day. We diagnosed periappendicitis based on the operative findings. This is the first report of periappendicitis with CD during adalimumab treatment.

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Disclosures

Conflict of Interest: All authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Gastroenterology, Saiseikai Central Hospital, Mita, Minato-Ku, Tokyo, Japan

    Shinta Mizuno, Atsushi Nakazawa, Ayumi Ogawa & Nobuhiro Tsukada

  2. Department of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-Ku, Tokyo, 160-8582, Japan

    Shinta Mizuno & Tadakazu Hisamatsu

  3. Department of Pathology, Saiseikai Central Hospital, Mita, Minato-Ku, Tokyo, Japan

    Shigemichi Hirose

Authors
  1. Shinta Mizuno
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  2. Atsushi Nakazawa
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  3. Ayumi Ogawa
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  4. Tadakazu Hisamatsu
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  5. Shigemichi Hirose
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  6. Nobuhiro Tsukada
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Correspondence to Shinta Mizuno.

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Mizuno, S., Nakazawa, A., Ogawa, A. et al. Periappendicitis during adalimumab treatment for ileocecal Crohn’s disease in a 29-year-old male. Clin J Gastroenterol 8, 134–137 (2015). https://doi.org/10.1007/s12328-015-0575-x

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  • DOI: https://doi.org/10.1007/s12328-015-0575-x

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