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Blastic Plasmacytoid Dendritic Cell Neoplasm: Still an Enigma

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References

  1. Petrella T, Bagot M, Willemze R et al (2005) Blastic NK-cell lymphomas (agranular CD4+CD56+hematodermic neoplasms): a review. Am J Clin Pathol 123:662

    Article  PubMed  Google Scholar 

  2. Chaperot L, Bendriss N, Manches O et al (2001) Identification of a leukemic counterpart of the plasmacytoid dendritic cells. Blood 97:3210

    Article  PubMed  CAS  Google Scholar 

  3. Reizis B, Bunin A, Ghosh HS et al (2011) Plasmacytoid dendritic cells: recent progress and open questions. Annu Rev Immunol 29:163

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Julia F, Petrella T, Beylot-Barry M et al (2013) Blastic plasmacytoid dendritic cell neoplasm: clinical features in 90 patients. Br J Dermatol 169:579

    Article  PubMed  CAS  Google Scholar 

  5. Falcone U, Sibai H, Deotare U (2016) A critical review of treatment modalities for blastic plasmacytoid dendritic cell neoplasm. Crit Rev Oncol Hematol 107:156–162

    Article  PubMed  Google Scholar 

  6. Lucioni M, Novara F, Fiandrino G et al (2011) Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion. Blood 118:4591

    Article  PubMed  CAS  Google Scholar 

  7. Rauh MJ, Rahman F, Good D et al (2012) Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation, lacking cutaneous involvement: case series and literature review. Leuk Res 36:81

    Article  PubMed  CAS  Google Scholar 

  8. Shapiro R, Sangle N, Keeney M, Chin-Yee IH, Hsia CC et al (2015) Blastic plasmacytoid dendritic cell neoplasm: a review of diagnosis, pathology, and therapy. J Cell Sci Ther S8:008. https://doi.org/10.4172/2157-7013.S8-008

    Article  Google Scholar 

  9. Petrella T, Meijer CJ, Dalac S, Willemze R, Maynadié M et al (2004) TCL1 and CLA expression in agranular CD4/CD56 hematodermic neoplasms (blastic NKcell lymphomas) and leukemia cutis. Am J Clin Pathol 122:307–313

    Article  PubMed  CAS  Google Scholar 

  10. Sangle NA, Schmidt RL, Patel JL, Medeiros LJ, Agarwal AM et al (2014) Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm. Mod Pathol 27:1137–1143

    Article  PubMed  CAS  Google Scholar 

  11. Julia F, Dalle S, Duru G, Balme B, Vergier B et al (2014) Blastic plasmacytoid dendritic cell neoplasms: clinico-immunohistochemical correlations in a series of 91 patients. Am J Surg Pathol 38:673–680

    Article  PubMed  Google Scholar 

  12. Facchetti F, Jones DM, Petrella T (2008) Blastic plasmacytoid dendritic cells neoplasm, WHO classification of tumours of hematopoietic and lymphoid tissues. IARC Press, Lyon, pp 145–147

    Google Scholar 

  13. Martin-Martin L, Lopez A, Vidriales B, Caballero MD, Rodrigues AS et al (2015) Classification and clinical behaviour of blastic plasmacytoid dendritic cell neoplasms according to their maturation-associated immunophenotypic profile. Oncotarget 6:19204–19216

    Article  PubMed  PubMed Central  Google Scholar 

  14. Angelot-Delettre F, Garnache-Ottou F (2012) Blastic plasmacytoid dendritic cell neoplasm. Blood 120:2784

    Article  PubMed  Google Scholar 

  15. Taylor J, Kim SS, Stevenson KE et al (2013) Loss-of-function mutations in the splicing factor ZRSR2 are common in blastic plasmacytoid dendritic cell neoplasm and have male predominance [ASH abstract 741]. Blood 122(21):741

    Google Scholar 

  16. Pagano L, Valentini CG, Pulsoni A, Fisogni S, Carluccio P et al (2013) Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study. Haematologica 98:239–246

    Article  PubMed  PubMed Central  Google Scholar 

  17. Tsagarakis NJ, Kentrou NA, Papadimitrou KA, Pagoni M, Kokkini G, for the Hellenic Dendritic Cell Leukemia Study Group et al (2010) Acute lymphoplasmacytoid dendritic cell (DC2) leukemia: results from the Hellenic Dendritic Cell Leukemia Study Group. Leuk Res 34:438–446

    Article  PubMed  CAS  Google Scholar 

  18. Poret E, Vidal C, Desbrosses Y et al (2015) How to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN) patients: results on 86 patients of the French BPDCN network. Blood 126:456

    Google Scholar 

  19. Pagano L, Valentini CG, Pulsoni A et al (2013) Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study. Haematologica 98:239

    Article  PubMed  PubMed Central  Google Scholar 

  20. Julia F, Petrella T, Beylot-Barry M (2013) Blastic plasmacytoid dendritic cell neoplasm: clinical features in 90 patients. Br J Dermatol 169(3):579–586

    Article  PubMed  CAS  Google Scholar 

  21. Frankel AE, Woo JH, Ahn C (2014) Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients. Blood 124(3):385–392

    Article  PubMed  PubMed Central  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology and Lab Services, Rajiv Gandhi Cancer Institute and Research Center, Rohini, Delhi, India

    Neha Singh, Poojan Agarwal & Anurag Mehta

  2. Department of Hemato-Oncology, Rajiv Gandhi Cancer Institute and Research Center, Rohini, Delhi, India

    Narendra Agrawal

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  1. Neha Singh
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  2. Narendra Agrawal
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  4. Anurag Mehta
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Correspondence to Neha Singh.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Singh, N., Agrawal, N., Agarwal, P. et al. Blastic Plasmacytoid Dendritic Cell Neoplasm: Still an Enigma. Indian J Hematol Blood Transfus 34, 568–572 (2018). https://doi.org/10.1007/s12288-018-0930-4

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  • DOI: https://doi.org/10.1007/s12288-018-0930-4

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