, Volume 24, Issue 3, pp 334–335 | Cite as

Wirkungsmechanismen toxischer und kanzerogener Metallverbindungen

Karriere, Köpfe & Konzepte Toxicology Award der Gesellschaft für Toxikologie (GT)


  1. [1]
    EFSA (2014) Dietary exposure to inorganic arsenic in the European population. EFSA J, doi: 10.2903/j.efsa.2014.3597Google Scholar
  2. [2]
    Beyersmann D, Hartwig A (2008) Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. Arch Toxicol 82:493–512CrossRefPubMedGoogle Scholar
  3. [3]
    Hartwig A (2001) Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function. Antioxid Redox Signal 3:625–634CrossRefPubMedGoogle Scholar
  4. [4]
    Hartwig A, Pelzer A, Asmuss M et al. (2003) Very low concentrations of arsenite suppress poly(ADP-ribosyl)ation in mammalian cells. Int J Cancer 104:1–6CrossRefPubMedGoogle Scholar
  5. [5]
    Hartwig A (2013) Metal interaction with redox regulation: an integrating concept in metal carcinogenesis? Free Radic Biol Med 55:63–72CrossRefPubMedGoogle Scholar
  6. [6]
    Strauch BM, Niemand RK, Winkelbeiner NL et al. (2017) Comparison between micro-and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells. Part Fibre Toxicol 14:28CrossRefPubMedPubMedCentralGoogle Scholar
  7. [7]
    Fischer BM, Neumann D, Piberger AL et al. (2016) Use of high-throughput RT-qPCR to assess modulations of gene expression profiles related to genomic stability and inter-actions by cadmium. Arch Toxicol 90:2745–2761CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Institut für Angewandte Biowissenschaften (IAB)Abteilung Lebensmittelchemie und Toxikologie Karlsruher Institut für Technologie (KIT)KarlsruheDeutschland

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