BIOspektrum

, Volume 23, Issue 7, pp 777–778 | Cite as

Zirkulierende extrazelluläre Vesikel - die Biomarker der Zukunft?!

Wissenschaft · Special: Molekulare Diagnostik Diagnostische Methoden
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Abstract

Extracellular vesicles (EV) are secreted by most cells and are present in every body fluid. They can be seen as major players in the regulation and communication of cells. They are adressed as therapeutic and diagnostic tool for many disorders including neurodegenerative diseases. Distinct subpopulations of platelet derived EVs have been shown to contain high concentrations of Alzheimer’s disease(AD)-associated proteins e. g. APP, APOE, lipids and miRNAs and thus might contribute actively to the progression of the disease.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2017

Authors and Affiliations

  1. 1.Biomedizinische ForschungLeibniz-Institut für Analytische Wißsenschaften (ISAS) e. V.DortmundDeutschland
  2. 2.Projektgruppe: Biomarker altersaßsoziierter Dysfunktionen und ErkrankungenLeibniz-Forschungsverbund Gesundes Altern, Leibniz-Institut für Analytische Wissenschaften (ISAS) e. V.DortmundDeutschland
  3. 3.Institut für Klinische Chemie und LaboratoriumsmedizinUniversität RegensburgRegensburgDeutschland

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