Table 1 Baseline characteristics of total cohort, patients with an ICS < 85 and ICS ≥ 85. Values are displayed as median (IQR) or n (%)
From: The Prognostic Value of a Validated and Automated Intravascular Ultrasound-Derived Calcium Score
| All patients N = 408 | ICS < 85 N = 204 | ICS ≥ 85 N = 204 | P value | |
|---|---|---|---|---|
| Patient level | ||||
| Age in years | 65.7 (57.2–72.2) | 62.7 (53.9–70.2) | 68.0 (61.1–74.2) | < 0.001 |
| Male gender | 296 (72.5%) | 147 (72.1%) | 149 (73.0%) | 0.82 |
| Hypertension | 260 (63.7%) | 115 (56.4%) | 145 (71.1%) | 0.002 |
| Hypercholesterolemia | 226 (55.4%) | 96 (47.1%) | 130 (63.7%) | 0.001 |
| Statin treatment | 233 (57.1%) | 106 (54.4%) | 127 (66.1%) | 0.018 |
| Diabetes mellitus | 84 (20.6%) | 34 (16.7%) | 50 (24.5%) | 0.050 |
| Positive familial history | 152 (37.3%) | 80 (39.2%) | 72 (35.3%) | 0.41 |
| Smoking | 165 (40.4%) | 86 (42.2%) | 79 (38.2%) | 0.48 |
| Previous MI | 104 (25.5%) | 52 (25.5%) | 52 (25.5%) | 1 |
| Previous PCI | 106 (26.1%) | 53 (26.0%) | 53 (26.0%) | 1 |
| Previous CABG | 16 (3.9%) | 7 (3.4%) | 9 (4.4%) | 0.61 |
| Previous stroke | 22 (5.4%) | 4 (2.0%) | 18 (8.8%) | 0.003 |
| Previous PAD | 42 (10.3%) | 13 (6.4%) | 29 (14.2%) | 0.006 |
| Renal impairment (eGFR < 60 ml/min) | 77 (18.9%) | 26 (13.7%) | 51 (25.8%) | 0.003 |
| eGFR (ml/min) | 79 (63–90) | 83 (68–93) | 74 (58–88) | < 0.001 |
| Presentation with ACS | 178 (43.6%) | 103 (50.5%) | 75 (36.8%) | 0.005 |
| Index treatment | 0.005 | |||
| PCI performed at baseline | 334 (81.9%) | 169 (82.8%) | 165 (80.9%) | |
| CABG performed at baseline | 19 (4.7%) | 3 (1.5%) | 16 (7.8%) | |
| Conservative treatment at baseline | 55 (13.5%) | 32 (15.7%) | 23 (11.3%) | |
| Vessel level | ||||
| Study vessel | 0.13 | |||
| Left anterior descending | 262 (64.2%) | 123 (60.3%) | 139 (68.1%) | |
| Left circumflex | 59 (14.5%) | 33 (16.2%) | 26 (12.7%) | |
| Right coronary artery | 77 (18.9%) | 45 (22.1%) | 32 (15.7%) | |
| Left main stem | 10 (2.5%) | 3 (1.5%) | 7 (3.4%) | |
| Study vessel revascularized at index procedure (either PCI or CABG) | 308 (75.5%) | 144 (71.1%) | 164 (80.9%) | 0.021 |