Table 1 Baseline characteristics of total cohort, patients with an ICS < 85 and ICS ≥ 85. Values are displayed as median (IQR) or n (%)

From: The Prognostic Value of a Validated and Automated Intravascular Ultrasound-Derived Calcium Score

  All patients N = 408 ICS < 85 N = 204 ICS ≥ 85 N = 204 P value
Patient level
  Age in years 65.7 (57.2–72.2) 62.7 (53.9–70.2) 68.0 (61.1–74.2) < 0.001
  Male gender 296 (72.5%) 147 (72.1%) 149 (73.0%) 0.82
  Hypertension 260 (63.7%) 115 (56.4%) 145 (71.1%) 0.002
  Hypercholesterolemia 226 (55.4%) 96 (47.1%) 130 (63.7%) 0.001
  Statin treatment 233 (57.1%) 106 (54.4%) 127 (66.1%) 0.018
  Diabetes mellitus 84 (20.6%) 34 (16.7%) 50 (24.5%) 0.050
  Positive familial history 152 (37.3%) 80 (39.2%) 72 (35.3%) 0.41
  Smoking 165 (40.4%) 86 (42.2%) 79 (38.2%) 0.48
  Previous MI 104 (25.5%) 52 (25.5%) 52 (25.5%) 1
  Previous PCI 106 (26.1%) 53 (26.0%) 53 (26.0%) 1
  Previous CABG 16 (3.9%) 7 (3.4%) 9 (4.4%) 0.61
  Previous stroke 22 (5.4%) 4 (2.0%) 18 (8.8%) 0.003
  Previous PAD 42 (10.3%) 13 (6.4%) 29 (14.2%) 0.006
  Renal impairment (eGFR < 60 ml/min) 77 (18.9%) 26 (13.7%) 51 (25.8%) 0.003
  eGFR (ml/min) 79 (63–90) 83 (68–93) 74 (58–88) < 0.001
  Presentation with ACS 178 (43.6%) 103 (50.5%) 75 (36.8%) 0.005
  Index treatment 0.005
   PCI performed at baseline 334 (81.9%) 169 (82.8%) 165 (80.9%)  
   CABG performed at baseline 19 (4.7%) 3 (1.5%) 16 (7.8%)  
   Conservative treatment at baseline 55 (13.5%) 32 (15.7%) 23 (11.3%)  
Vessel level
  Study vessel 0.13
   Left anterior descending 262 (64.2%) 123 (60.3%) 139 (68.1%)  
   Left circumflex 59 (14.5%) 33 (16.2%) 26 (12.7%)  
   Right coronary artery 77 (18.9%) 45 (22.1%) 32 (15.7%)  
   Left main stem 10 (2.5%) 3 (1.5%) 7 (3.4%)  
  Study vessel revascularized at index procedure (either PCI or CABG) 308 (75.5%) 144 (71.1%) 164 (80.9%) 0.021
  1. ACS acute coronary syndrome, BMS bare metal stent, BRS bioresorbable scaffold, CABG coronary artery bypass graft, DES drug-eluting stent, eGFR estimated glomerular filtration rate, ICS IVUS-calcium score, IQR interquartile range, IVUS intravascular ultrasound, MI myocardial infarction, PAD peripheral artery disease, PCI percutaneous coronary intervention