Skip to main content
Log in

Melatonin and ST Segment Elevation Acute Myocardial Infarction—the “Forgotten Cardioprotective Therapy” Strikes Again

  • Letter to the Editor
  • Published:
Journal of Cardiovascular Translational Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Rosenberg, J. H., Werner, J. H., Moulton, M. J., & Agrawal, D. K. (2018). Current modalities and mechanisms underlying cardioprotection by ischemic conditioning. Journal of Cardiovascular Translational Research. https://doi.org/10.1007/s12265-018-9813-1.

  2. Dominguez-Rodriguez, A., Abreu-Gonzalez, P., & Reiter, R. J. (2017). Melatonin for cardioprotection in ST elevation myocardial infarction: are we ready for the challenge? Heart, 103(9), 647–648. https://doi.org/10.1136/heartjnl-2016-310689.

    Article  PubMed  Google Scholar 

  3. Zhou, H., Ma, Q., Zhu, P., Ren, J., Reiter, R. J., & Chen, Y. (2018). Protective role of melatonin in cardiac ischemia-reperfusion injury: from pathogenesis to targeted therapy. Journal of Pineal Research, 64(3). https://doi.org/10.1111/jpi.12471.

  4. Dominguez-Rodriguez, A., Abreu-Gonzalez, P., de la Torre-Hernandez, J. M., et al. (2017). Effect of intravenous and intracoronary melatonin as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: results of the Melatonin Adjunct in the acute myocaRdial Infarction treated with Angioplasty trial. Journal of Pineal Research, 62(1). https://doi.org/10.1111/jpi.12374.

  5. Dominguez-Rodriguez, A., Abreu-Gonzalez, P., de la Torre-Hernandez, J. M., et al. (2017). Usefulness of early treatment with melatonin to reduce infarct size in patients with ST-segment elevation myocardial infarction receiving percutaneous coronary intervention (from the Melatonin Adjunct in the Acute Myocardial Infarction Treated With Angioplasty Trial). The American Journal of Cardiology, 120(4), 522–526. https://doi.org/10.1016/j.amjcard.2017.05.018.

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

The authors thank Ines Abreu-Afonso for her linguistic revision of this manuscript.

Funding

This research was funded by the Institute Carlos III (ISCIII) (PI15/01260), General Branch Evaluation and Research Promotion, State Plan of Scientific and Technical Research and Innovation 2013–2016, and European Regional Development Fund Health–FEDER.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alberto Dominguez-Rodriguez.

Ethics declarations

Conflict of Interest

A.D-R and P.A-G have a patent to the use of melatonin in ST-elevation myocardial infarction (P201400743). The other author reports no conflict of interest.

Ethical Approval

This article does not contain any studies with humans neither with animals.

Additional information

Associate Editor Junjie Xiao oversaw the review of this article

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Dominguez-Rodriguez, A., Baez-Ferrer, N. & Abreu-Gonzalez, P. Melatonin and ST Segment Elevation Acute Myocardial Infarction—the “Forgotten Cardioprotective Therapy” Strikes Again. J. of Cardiovasc. Trans. Res. 11, 308–309 (2018). https://doi.org/10.1007/s12265-018-9815-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12265-018-9815-z

Navigation