Neuroscience Bulletin

, Volume 34, Issue 3, pp 546–548 | Cite as

A Rarely Encountered Case: A Patient with Primary Pituitary Tuberculosis and Stroke

  • Min Chen
  • Chengru Song
  • Hongbo Liu
Letter to the Editor

Dear Editor,

Infections are a common cause of stroke, and tuberculosis is one of the most dangerous causes of central nervous system (CNS) diseases [1]. For example, cerebral infarction is a relatively common and serious CNS disease associated with tuberculosis [2]. Patients with intrasellar tuberculosis are extremely rare [3], and stroke caused by primary pituitary tuberculosis has not yet been reported.

The present case report describes a 52-year-old Chinese man who was referred to the Neurology Clinic with a 3-month history of fluctuating bitemporal headache, fatigue, nausea, anorexia, and several instances of fever. The patient had no history of cough and exhibited no weight loss, visual field defects, diminution of vision, or contact history of tuberculosis. Two months before the patient presented at our department, he was admitted to a local hospital due to bitemporal headache. His brain magnetic resonance imaging (MRI) scan was normal apart from a slightly enlarged pituitary....


  1. 1.
    Erdem H, Inan A, Guven E, Hargreaves S, Larsen L, Shehata G, et al. The burden and epidemiology of community–acquired central nervous system infections: a multinational study. Eur J Clin Microbiol Infect Dis 2017, 36:1595–1611.CrossRefPubMedGoogle Scholar
  2. 2.
    Wasay M, Farooq S, Khowaja ZA, Bawa ZA, Ali SM, Awan S, et al. Cerebral infarction and tuberculoma in central nervous system tuberculosis: frequency and prognostic implications. J Neurol Neurosurg Psychiatry 2014, 85: 1260–1264.CrossRefPubMedGoogle Scholar
  3. 3.
    Majumdar K, Barnard M, Ramachandra S, Berovic M, Powell M. Tuberculosis in the pituitary fossa: a common pathology in an uncommon site. Endocrinol Diabetes Metab Case Rep 2014, 2014: 140091.PubMedPubMedCentralGoogle Scholar
  4. 4.
    Li J, Wang Y. Blood biomarkers in minor stroke and transient ischemic attack. Neurosci Bull 2016, 32: 463–468.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Leonard JM. Central nervous system tuberculosis. Microbiol Spectr 2017, 5.Google Scholar
  6. 6.
    Maurice-Williams RS. Tuberculomas of the brain in Britain. Postgrad Med J 1972, 48: 678–681.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    DeAngelis LM. Intracranial tuberculoma: case report and review of the literature. Neurology 1981, 31: 1133–1136.CrossRefPubMedGoogle Scholar
  8. 8.
    Deogaonkar M, De R, Sil K, Das S. Pituitary tuberculosis presenting as pituitary apoplexy. Int J Infect Dis 2006, 10: 338–339.CrossRefPubMedGoogle Scholar
  9. 9.
    Pereira J, Vaz R, Carvalho D, Cruz C. Thickening of the pituitary stalk: a finding suggestive of intrasellar tuberculoma? Case report. Neurosurgery 1995, 36: 1013–1015.PubMedGoogle Scholar
  10. 10.
    van Timmeren MM, Heeringa P, Kallenberg CG. Infectious triggers for vasculitis. Curr Opin Rheumatol 2014, 26: 416–423.CrossRefPubMedGoogle Scholar

Copyright information

© Shanghai Institutes for Biological Sciences, CAS and Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of Neurology, First Affiliated HospitalZhengzhou UniversityZhengzhouChina
  2. 2.Department of MRI, First Affiliated HospitalZhengzhou UniversityZhengzhouChina

Personalised recommendations