Potential Role of Magnesium in Cancer Initiation and Progression

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References

  1. 1.

    Grober U, Schmidt J, Kisters K (2015) Magnesium in prevention and therapy. Nutrients 7(9):8199–8226

    Article  Google Scholar 

  2. 2.

    Hosthor SS, Mahesh P, Priya SM, Sharada P, Jyotsna M, Chitra S (2014) Quantitative analysis of serum levels of trace elements in patients with oral submucous fibrosis and oral squamous cell carcinoma: a randomized cross – sectional study. J Oral MaxillfacPathol 18:46–51

    Google Scholar 

  3. 3.

    Mendes PMV, Bezerra DLC, Santos LRD, Santos LDO, Melo SRDS, Morais JBS et al (2018) Magnesium in breast Cancer: what is its influence on the progression of this disease? Biol Trace Elem Res 184(2):334–339

    CAS  Article  Google Scholar 

  4. 4.

    Bertinato J, Xiao CW, Ratnayake WM et al (2015) Lower serum magnesium concentration is associated with diabetes, insulin resistance, and obesity in south Asian and white Canadian women but not men. Food Nutr Res 59(1):25974

    Article  Google Scholar 

  5. 5.

    Abdelgawad IA, El-Mously RH, Saber MM, Mansour OA, Shouman SA (2015) Significance of serum levels of vitamin D and some related minerals in breast cancer patients. Int J Clin Exp Pathol 8(4):4074–4082

    CAS  PubMed  PubMed Central  Google Scholar 

  6. 6.

    Anastassopoulou J, Theophanides T (2015) Magnesium-DNA interactions and the possible relation of magnesium to carcinogenesis. Irradiation and free radicals. Crit Rev Oncol Hematol 42(1):79–91

    Article  Google Scholar 

  7. 7.

    Karki K, Pande D, Negi R, Khanna S, Khanna RS, Khanna HD (2015) Association between biomarkers of oxidative stress, trace elements, and cell proliferation index in patients with benign and malignant breast diseases. J Environ Pathol Toxicol Oncol 34(1):1–10

    Article  Google Scholar 

  8. 8.

    Karki K, Pande D, Negi R, Khanna S, Khanna RS, Khanna HD (2015) Correlation of serum toll like receptor 9 and trace elements with lipid peroxidation in the patients of breast diseases. J Trace Elem Med Biol 30:11–16

    CAS  Article  Google Scholar 

  9. 9.

    Castiglioni S, Maier JA (2011) Magnesium and cancer : adangerous liason. Magnes Res 24(3):92–100

    Article  Google Scholar 

  10. 10.

    Yu E, Ahn YS, Jang SJ, Kim MJ, Yoon HS, Gong G, Choi J (2007) Overexpression of the wip1 gene abrogates the p38 MAPK/p53/ Wip1 pathway and silences p16 expression in human breast cancers. Breast Cancer Res Treat 101(3):269–278

    CAS  Article  Google Scholar 

  11. 11.

    Bagulkar BB, Chaudhary M, Gawande M, Patil S, Gadbail A, Bagulkar S (2013) Colorimetric determination of magnesium in blood and saliva in Oral squamous cell carcinoma and potentially malignant disorders by titan yellow method. J Orofac Res 3(4):240–244

    Article  Google Scholar 

  12. 12.

    Aziz NZ, Arathi K, Prasad BG, Desai D, Shetty SJ, Shahid M (2018) Evaluation of magnesium levels in blood and saliva of oral squamous cell carcinoma and potentially malignant disorders by xylidyl blue method. J Oral Maxillofac Pathol 22(1):147–162

    PubMed  PubMed Central  Google Scholar 

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Correspondence to Archana A. Gupta.

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Gupta, A.A., Shekatkar, M., Raj, A.T. et al. Potential Role of Magnesium in Cancer Initiation and Progression. Pathol. Oncol. Res. 26, 2001–2002 (2020). https://doi.org/10.1007/s12253-019-00750-w

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