Abstract
A very rare clinical entity, so-called eosinophilic meningitis, classified by prevalence of eosinophils in cerebrospinal fluid (CSF), with the presence of pleiocytosis, has been recorded in our laboratory four times only in the last 24 years. A low glucose level, elevation of total protein and lactic acid in CSF were detected in all the clinical cases. The last two cases were made possible by using flow cytometry method; surprisingly, the presence was found in mature T-cells in CSF, predominantly helpers (CD3+, CD4+) and, practically, none is B-cells (CD19+), plasma cells (CD138+) and NK-cells.
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Abbreviations
- CSF:
-
cerebrospinal fluid
References
Adam P., Táborský L., Průcha M., Sobek O., Kratochvíla J., Zeman D.: Cerebrospinal Fluid Cytology. Medica News Publishers, Prague 2001a.
Adam P., Táborský L., Sobek O., Hildebrand T., Kelbich P, Průcha M., Hyánek J.: Cerebrospinal fluid. Adv.Clin.Chem. 36, 1–62 (2001b).
Adam P., Sobek O., Scott C.S.: Analysis of cerebrospinal fluid cell populations with monoclonal antibodies. Folia Microbiol. 52, 529–534 (2007).
Adam P., Sobek O., Scott C.S.: Immunophenotypic analysis of cerebrospinal fluid cell populations with the Cell-Dyn Sapphire haematology analyser: method feasibility and preliminary observations. Internat.J.Lab.Haematol., in press (2009).
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Adam, P., Sobek, O., Hybel’ová, M. et al. Eosinophilic meningitis — an immunophenotyping recording of a very rare clinical entity — Brief Report . Folia Microbiol 54, 257–260 (2009). https://doi.org/10.1007/s12223-009-0040-7
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DOI: https://doi.org/10.1007/s12223-009-0040-7