Abstract
The influence of age and physique on dual-energy X-ray absorptiometry (DXA) and quantitative ultrasound (QUS) was investigated in young, middle-aged, and older women. The validity of the bilateral calcaneal QUS values was investigated regarding the bone mineral density (BMD) values on DXA of the lumbar spine, left femoral neck, and left femur as the optimal standards. The subjects were 55 young women (19.6 ± 1.0 years), and 152 middle-aged and older women (62.9 ± 7.2 years). The BMD on DXA was significantly correlated with the bone strength on QUS in both young and middle-aged or older women, but the positive likelihood ratios of the standard QUS values recommended by the manufacturer to the optimum standards on DXA were low, suggesting that osteoporosis cannot be diagnosed or predicted by use of the QUS method. Combination with DXA is necessary, such as primary screening by QUS followed by secondary screening by DXA.
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References
Yoshimura N. Incidences of fast bone losers and factors affecting changes in bone mineral density. A cohort study in a rural Japanese community. J Bone Miner Metab. 1996;14:171–7.
Yamazaki K, Kushida K, Ohmura A, Sano M, Inoue T. Ultrasound bone densitometry of the os calcis in Japanese women. Osteoporos Int. 1994;4:220–5.
Sakata S, Kushida K, Yamazaki K, Inoue T. Ultrasound bone densitometry of os calsis in elderly Japanese women with hip fracture. Calcif Tissue Int. 1997;60:2–7.
Schott AM, Hans D, Sornay-Rendu E, Delmas PD, Meunier PJ. Ultrasound measurements on os calcis: precision and age-related changes in a normal female population. Osteoporos Int. 1993;3(5):249–54.
Williams JW Jr, Simel DL. The rational clinical examination. Does this patient have ascites? How to divine fluid in the abdomen. JAMA. 1992;267(19):2645–8.
Guarino JR, Guarino JC. Auscultatory percussion: a simple method to detect pleural effusion. J Gen Intern Med. 1994;9(2):71–4.
Farwell JR, Dohrmann GJ, Flannery JT. Intracranial neoplasms in infants. Arch Neurol. 1978;35(8):533–7.
Deyo RA, Rainville J, Kent DL. What can the history and physical examination tell us about low back pain? JAMA. 1992;268(6):760–5.
Williams JW Jr, Simel DL. Does this patient have sinusitis? Diagnosing acute sinusitis by history and physical examination. JAMA. 1993;270(10):1242–6.
Bush B, Shaw S, Cleary P, Delbanco TL, Aronson MD. Screening for alcohol abuse using the CAGE questionnaire. Am J Med. 1987;82(2):231–5.
Grover SA, Barkun AN, Sackett DL. The rational clinical examination. Does this patient have splenomegaly? JAMA. 1993;270(18):2218–21.
Froehling DA, Silverstein MD, Mohr DN, Beatty CW. The rational clinical examination. Does this dizzy patient have a serious form of vertigo? JAMA. 1994;271(5):385–8.
J Health Welf Stat. 2004;51(9):434 (in Japanese).
Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn’t. 1996. Clin Orthop Relat Res. 2007;455:3–5.
Ikeda Y, Iki M, Morita A, Aihara H, Kagamimori S, Kagawa Y, et al. Ultrasound bone densitometry of the calcaneus, determined with Sahara, in healthy Japanese adolescents: Japanese Population-based Osteoporosis (JPOS) Study. J Bone Miner Metab. 2004;22(3):248–53.
Mishell DR Jr. Reproductive endocrinology. In: Comprehensive gynecology. 2nd ed. St. Louis:Mosby, Inc. 1994. p. 79–140.
Manolagas SC, Jilka RL. Cytokines hematopoiesis, osteoclastogenesis and estrogens. Calcif Tiisue int. 1992;50:199–202.
Neu CM, Rauch F, Manz F, Schoenau E. Modeling of cross-sectional bone size, mass and geometry at the proximal radius: a study of normal bone development using peripheral quantitative computed tomography. Osteoporos Int. 2001;12(7):538–47.
Ashman RB, Corin JD, Turner CH. Elastic properties of cancellous bone: measurement by an ultrasonic technique. J Biomech. 1987;20(10):979–86.
Zagzebski JA, Rossman PJ, Mesina C, Mazess RB, Madsen EL. Ultrasound transmission measurements through the os calcis. Calcif Tissue Int. 1991;49(2):107–11.
Langton CM, Palmer SB, Porter RW. The measurement of broadband ultrasonic attenuation in cancellous bone. Eng Med. 1984;13(2):89–91.
Wallach S, Feinblatt JD, Carstens JH Jr, Avioli LV. The bone “quality” problem. Calcif Tissue Int. 1992;51(3):169–72.
Nagasawa S, Miyake T, Yokoyama E, Nozaki S. The relationship between calcaneus bone mineral density, physique, and daily habits in junior-high school students. J Nihon Univ Med Assoc. 2001;60(11):485–91.
Hung VW, Qin L, Au SK, Choy WY, Leung KS, Leung PC, et al. Correlations of calcaneal QUS with pQCT measurements at distal tibia and non-weight-bearing distal radius. J Bone Miner Metab. 2004;22(5):486–90.
Imashuku Y, Takada M, Murata K. Comparisons of bone mass measurements on various skeletal sites including quantitative ultrasonography of the calcaneus for assessing age-related losses, their correlations, and diagnostic agreement using the Japanese and WHO criteria for osteoporosis. Radiat Med. 2007;25(4):148–54.
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Iida, T., Chikamura, C., Aoi, S. et al. A study on the validity of quantitative ultrasonic measurement used the bone mineral density values on dual-energy X-ray absorptiometry in young and in middle-aged or older women. Radiol Phys Technol 3, 113–119 (2010). https://doi.org/10.1007/s12194-010-0086-x
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DOI: https://doi.org/10.1007/s12194-010-0086-x