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International Journal of Hematology

, Volume 109, Issue 6, pp 633–640 | Cite as

JSH practical guidelines for hematological malignancies, 2018: III. Myeloma-2. Related disorders of multiple myeloma

  • Shinsuke IidaEmail author
  • Chihiro Shimazaki
  • Masahiro Abe
  • Chiaki Nakaseko
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Solitary plasmacytoma

Introduction

In the International Myeloma Working Group (IMWG) classification, solitary plasmacytomas of bone or soft tissue are defined as meeting the four criteria of (1) biopsy-proven plasmacytoma of bone or soft tissue with evidence of clonal plasma cells, (2) normal bone marrow with no evidence of clonal plasma cells, (3) normal bone X-ray and MRI (or CT) of spine and pelvis (except for the solitary plasmacytoma lesion), and (4) absence of end-organ damage such as hypercalcemia, renal insufficiency, anemia, or bone lesions (CRAB) [1]. Solitary plasmacytomas of bone or soft tissue with minimal marrow involvement are further defined as meeting the four criteria of (1) biopsy-proven plasmacytoma of bone or soft tissue with evidence of clonal plasma cells, (2) clonal bone marrow plasma cells < 10%, (3) normal bone X-ray and MRI (or CT) of spine and pelvis (except for the solitary plasmacytoma lesion), and (4) absence of CRAB [1].

Solitary soft tissue...

Copyright information

© Japanese Society of Hematology 2019

Authors and Affiliations

  • Shinsuke Iida
    • 1
    Email author
  • Chihiro Shimazaki
    • 2
  • Masahiro Abe
    • 3
  • Chiaki Nakaseko
    • 4
  1. 1.Department of Hematology and OncologyNagoya City University Graduate School of Medical SciencesNagoyaJapan
  2. 2.Japan Community Health Care Organization Kyoto Kuramaguchi Medical CenterKyotoJapan
  3. 3.Department of Hematology, Endocrinology, and Metabolism, Institute of Biomedical SciencesTokushima University Graduate SchoolTokushimaJapan
  4. 4.Department of Hematology, School of MedicineInternational University of Health and WelfareNaritaJapan

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