International Journal of Hematology

, Volume 106, Issue 6, pp 729–731 | Cite as

Megakaryoblastic transformation of therapy-related myeloid neoplasms with concomitant MYC amplification on double minute chromosomes

  • Katsuya Yamamoto
  • Kimikazu Yakushijin
  • Yumiko Inui
  • Shinichiro Kawamoto
  • Kazuyoshi Kajimoto
  • Yoshitake Hayashi
  • Hiroshi Matsuoka
  • Hironobu Minami
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Keywords

Megakaryoblastic transformation MYC amplification Double minute chromosomes Therapy-related myeloid neoplasms 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Reference

  1. 1.
    Huh YO, Tang G, Talwalkar SS, Khoury JD, Ohanian M, Bueso-Ramos CE, et al. Double minute chromosomes in acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia are associated with micronuclei, MYC or MLL amplification, and complex karyotype. Cancer Genet. 2016;209:313–20.CrossRefPubMedGoogle Scholar

Copyright information

© The Japanese Society of Hematology 2017

Authors and Affiliations

  • Katsuya Yamamoto
    • 1
  • Kimikazu Yakushijin
    • 1
  • Yumiko Inui
    • 1
  • Shinichiro Kawamoto
    • 1
  • Kazuyoshi Kajimoto
    • 2
  • Yoshitake Hayashi
    • 3
  • Hiroshi Matsuoka
    • 1
  • Hironobu Minami
    • 1
  1. 1.Division of Medical Oncology/Hematology, Department of MedicineKobe University Graduate School of MedicineKobeJapan
  2. 2.Department of PathologyHyogo Cancer CenterAkashiJapan
  3. 3.Division of Molecular Medicine and Medical Genetics, Department of PathologyKobe University Graduate School of MedicineKobeJapan

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