Zusammenfassung
Die AV-Knoten-Reentry-Tachykardien (AVNRT) sind gutartige, anfallsartig auftretende supraventrikuläre Tachykardien und durch einen plötzlichen Beginn und Ende charakterisiert. Ursächlich besteht eine sog. funktionelle Längsdissoziation des AV-Knotens mit schnell und langsam leitenden Anteilen. Das EKG zeigt eine regelmäßige Tachykardie mit schmalem QRS-Komplex. Die Akuttherapie umfasst zunächst vagale Manöver (Karotisdruck etc.) oder die Bolusgabe von Adenosin i.v. Zur Rezidivprophylaxe spielt heute die dauerhafte Medikamenteneinnahme keine Rolle mehr. Die Katheterablation des langsamen Leitungsweges ist die Therapie der ersten Wahl bei rezidivierend symptomatischen Patienten. Die Erfolgsraten liegen bei annähernd 100%, die Komplikationen eines hochgradigen AV-Blocks mit Schrittmacherbedürftigkeit bei <1%. Die Häufigkeit einer AVNRT-Ablation bezogen auf alle durchgeführten Katheterablationen in Deutschland liegt bei fast 25%.
Abstract
Atrioventricular nodal reciprocating tachycardia (AVNRT) is the most common form of paroxysmal supraventricular tachycardia. It is characterized by palpitations, dizziness and pulsation at the neck. It is more common in females. AVNRT involves reciprocation between two functionally and anatomically distinct pathways within the perinodal atrial tissue. They extend as a fast pathway superior to Koch’s triangle and as a slow pathway infero-posterior to the compact AV node. Electrocardiography (ECG) during AVNRT shows a regular tachycardia with narrow QRS complexes. Acute treatment involves vagal maneuvers and intravenous adenosine. Catheter ablation targeting the slow pathway is the treatment of choice in symptomatic patients with recurrent episodes of AVNRT. Success rates are as high as almost 100%, whereas the complication rate is low. The only significant complication is a <1% incidence of third-degree AV block. Catheter ablation in AVNRT is performed in almost 25% of all ablation procedures in Germany.
Literatur
Anderson RH, Ho SY (1998) The architecture of the sinus node, the atrioventricular conduction axis, and the internodal atrial myocardium. J Cardiovasc Electrophysiol 9:1233–1248
Baker JH, Blumb VJ, Epstein AE et al (1994) Predictors of recurrent atrioventricular modal reentry after selective slow pathway ablation. Am J Cardiol 73:765–769
Becker T, Strauss M, Kleemann T et al (2008) Is there still a role for AV node ablation in patients with atrial fibrillation today? Eur Heart J 29:542
Bogun F, Knight B, Weiss R et al (1996) Slow pathway ablation in patients with documented but noninducible paroxysmal supraventricular tachycardia. J Am Coll Cardiol 28:1000–1004
Denes P, Wu D, Dhingra RC (1973) Demonstration of dual A-V nodal pathways in patients with paroxysmal supraventricular tachycardia. Circulation 48:549–555
Epstein LM, Lesh MD, Griffin JC et al (1995) A direct midseptal approach to slow atrioventricular nodal pathway ablation. PACE 18:57–64
Haissaguerre M, Warin JF, Lemetayer P et al (1989) Closed-chest ablation of retrograde conduction in patients with atrioventricular nodal reentrant tachycardia. N Engl J Med 320:426–433
Haissaguerre M, Gaita F, Fischer B et al (1992) Elimination of atrioventricular nodal reentrant tachycardia using discrete slow potentials to guide application of radiofrequency energy. Circulation 85:2162–2175
Hirao K, Otomo K, Wang X et al (1996) Para-hisian pacing – a new method for differentiating retrograde conduction over an accessory AV pathway from conduction over the AV node. Circulation 94:1027–1035
Jackman WM, Beckman KJ, McClelland HJ et al (1992) Treatment of supraventricular tachycardia due to atrioventricular nodal reentry by radiofrequency catheter ablation of slow pathway conduction. N Engl J Med 327:313–318
Jazayeri MR, Hempe SL, Sra JS et al (1992) Selective transcatheter ablation of the fast and slow pathways using radiofrequency energy in patients with atrioventricular nodal reentrant tachycardia. Circulation 85:1318–1328
Kalbfleisch SJ, Strickberger SA, Williamson B et al (1994) Randomized comparison of anatomic and electrogram mapping approaches to ablation of the slow pathway of atrioventricular node reentrant tachycardia. J Am Coll Cardiol 23:716–723
Kuck KH, Ernst S, Dorwarth U et al (2007) Leitlinien zur Katheterablation. Clin Res Cardiol 96:833–849
Langberg JJ, Leon A, Borganelli M et al (1993) A randomized, prospective comparison of anterior and posterior approaches to radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia. Circulation 87:1551–1556
Mitrani RD, Klein LS, Hackett FK et al (1993) Radiofrequency ablation for atrioventricular node reentrant tachycardia: comparison between fast (anterior) and slow (posterior) pathway ablation. J Am Coll Cardiol 21:432–441
Pfeiffer D, Tebbenjohanns J, Schumacher B et al (1994) Methoden, Topographie und Mechanismen der Radiofrequenzablation von AV-Knoten-Reentry-Tachykardien. Z Kardiol 83:877–886
Schumacher B, Tebbenjohanns J, Pfeiffer D et al (1995) Junktionale Arrhythmien bei der Radiofrequenzmodifikation des atrioventrikulären Knotens. Z Kardiol 84:977–985
Steven S, Rostock T, Hoffmann BA et al (2009) Favorable outcome using an abbreviated procedure for catheter ablation of AVNRT: results from a prospective randomized trial. J Cardiovasc Electrophysiol 20:522–525
Tai CT, Chen SA, Chiang CE et al (1996) Electrophysiologic characteristics and radiofrequency catheter ablation in patients with multiple atrioventricular nodal reentry tachycardias. Am J Cardiol 77:52–58
Tebbenjohanns J, Pfeiffer D, Schumacher B et al (1995) Impact of the local atrial electrogram in AV nodal reentrant tachycardia: Ablation versus modification of the slow pathway. J Cardiovasc Electrophysiol 6:245–251
Willems S, Eckhardt L, Hoffmann E et al (2007) Leitlinie invasive elektrophysiologische Diagnostik. Clin Res Cardiol 96:634–651
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Tebbenjohanns, J., Rühmkorf, K. Diagnostik und interventionelle Behandlung von AV-Knoten-Reentry-Tachykardien. Kardiologe 3, 296–308 (2009). https://doi.org/10.1007/s12181-009-0202-5
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DOI: https://doi.org/10.1007/s12181-009-0202-5