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Simultaneous Solid-Phase Extraction and Determination of Three Bisphenols in Water Samples and Orange Juice by a Porous β-Cyclodextrin Polymer

Abstract

A porous β-cyclodextrin polymer (P-CDP) was used as a new sorbent for simultaneous solid-phase extraction (SPE) and determination of bisphenol A (BPA), bisphenol F (BPF), and bisphenol AF (BPAF). The P-CDP was obtained via the cross-linking of β-cyclodextrin with tetrafluoroterephthalonitrile, and then was characterized by FT-IR spectroscopy, scanning electron microscopy, nitrogen adsorption-desorption isotherms, and thermo-gravimetric analysis. Adsorption tests showed that the P-CDP had good binding ability and fast uptake kinetics for three bisphenols. When used as a SPE sorbent for three bisphenols, P-CDP showed high extraction efficiencies, high enrichment factors, and good reusability. Based on the P-CDP sorbent, a new SPE-HPLC-UV method was developed and successfully applied to the detection of three bisphenols in real samples. The recoveries of BPF, BPA, and BPAF in water samples were 91.2–102.6% (RSD = 1.4–2.9%), 98.0–101.2% (RSD = 1.3–2.7%), and 96.3%–103.7% (RSD = 1.3–2.9%), respectively. Moreover, the recoveries of BPF, BPA, and BPAF in orange juice were 94.3–97.1% (RSD = 1.4–2.9%), 102.7–103.6% (RSD = 1.7–3.5%), and 94.5–101.0% (RSD = 1.3–2.8%), respectively. The limits of detection (S/N = 3) and the limits of quantification (S/N = 10) for all analytes were 0.3 and 1.0 ng/mL, respectively. Therefore, P-CDP can be used as a good SPE sorbent for the simultaneous determination of BPA, BPF, and BPAF in environmental water samples and beverages.

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Acknowledgements

This work was supported by the National Nature Science Foundation of China (21277106) and the Science and Technology Program of Wuhan (2015060101010034).

Funding

Dr. Qiang Wang has received research grant from the National Natural Science Foundation of China. Dr. Chiyang He has research grant from the Science and Technology Program of Wuhan.

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Correspondence to Chiyang He.

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Yarong Li declares that she has no conflict of interest. Pengpeng Lu declares that he has no conflict of interest. Jincheng Cheng declares that she has no conflict of interest. Qiang Wang declares that he has no conflict of interest. Chiyang He declares that he has no conflict of interest.

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This article does not contain any studies with human participants performed by any of the authors.

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Li, Y., Lu, P., Cheng, J. et al. Simultaneous Solid-Phase Extraction and Determination of Three Bisphenols in Water Samples and Orange Juice by a Porous β-Cyclodextrin Polymer. Food Anal. Methods 11, 1476–1484 (2018). https://doi.org/10.1007/s12161-017-1131-8

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Keywords

  • Porous β-cyclodextrin polymer
  • Solid-phase extraction
  • Bisphenols
  • Water samples
  • Beverage
  • High-performance liquid chromatography