Food Analytical Methods

, Volume 10, Issue 6, pp 1922–1930 | Cite as

Quartz-Wool-Supported Surface Dummy Molecularly Imprinted Silica as a Novel Solid-Phase Extraction Sorbent for Determination of Bisphenol A in Water Samples and Orange Juice

  • Yarong Li
  • Jincheng Cheng
  • Pengpeng Lu
  • Wang Guo
  • Qiang Wang
  • Chiyang He


A type of quartz wool-supported surface dummy molecularly imprinted silica (QW@MIP) was prepared using bisphenol AF as the template molecule for solid-phase extraction of bisphenol A (BPA). The QW@MIP was characterized by FT-IR spectroscopy, scanning electron microscopy, and thermo-gravimetric analysis. The adsorption tests showed that the QW@MIP had high-adsorption ability and a fast binding kinetics for BPA. When used as a solid-phase extraction (SPE) sorbent for BPA, the QW@MIP showed ease of packing SPE cartridge, low flow resistance, high extraction efficiency, high enrichment factor, and good reusability. Moreover, the dummy-imprinting technique used herein can effectively avoid the interference of residual template molecules in sorbent to determination of BPA. A new SPE method was developed using the QW@MIP sorbent, and then coupled with a high-performance liquid chromatography method, it was successfully applied to the detection of BPA spiked in water samples and orange juice and that in a certified sample with recoveries of 96.7–103.1% (RSD = 1.0–2.8%), 96.9–99.9% (RSD = 1.0–2.9%), and 99.2% (RSD = 0.5%), respectively. The limit of detection (S/N = 3) and limit of quantification (S/N = 10) for all samples were 0.05 and 0.17 ng mL−1, respectively. The QW@MIP can be potentially used as a good SPE sorbent for BPA in environmental water samples and beverages.


Quartz wool Dummy molecular imprinting Solid-phase extraction Bisphenol A High-performance liquid chromatography 



This work was supported by the National Nature Science Foundation of China (21277106) and the Science and Technology Program of Wuhan (2015060101010034).

Compliance with Ethical Standards


Dr. Qiang Wang has received research grant from the National Natural Science Foundation of China. Dr. Chiyang He has research grant from the Science and Technology Program of Wuhan.

Conflict of Interest

Yarong Li declares that she has no conflict of interest. Jincheng Cheng declares that she has no conflict of interest. Pengpeng Lu declares that he has no conflict of interest. Wang Guo declares that he has no conflict of interest. Qiang Wang declares that he has no conflict of interest. Chiyang He declares that he has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.School of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhanChina

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