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Prévalence du virus de l’hépatite C au Burundi : enquête nationale

Prevalence of hepatitis C virus in Burundi: a nationwide survey

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Journal Africain d'Hépato-Gastroentérologie

Résumé

Introduction

La prévalence du virus de l’hépatite C (VHC) n’est pas bien connue au Burundi. Des études parcellaires rapportent des taux variés. Aucune étude couvrant le territoire national n’avait été faite.

But

Déterminer la prévalence des anticorps anti virus de l’hépatite C (AcVHC) au Burundi.

Méthodes

Lors d’une enquête nationale de séroprévalence du VIH menée par le CEFORMI du CHU Kamenge en 2002, entre 2 et 4 ml de sérum et de plasma ont été décantés pour chaque échantillon puis conservés à -20°C pour usage ultérieur. Nous avons repris et analysé ces échantillons.

Résultats

Au total, 5569 individus ont été enrôlées, 2660 (47,8%) hommes et 2909 (52,2%) femmes. L’âge moyen était de 31±15 ans avec une médiane de 28 ans. Au niveau national, la prévalence globale des AcVHC était de 8,2%. Elle était de 8,3% chez l’homme et de 8,1% chez la femme. Selon les strates, la prévalence était de 10% en zone urbaine, de 9,1% en zone semi-urbaine et de 7,4% en zone rural. La co-infection avec le VIH était de 1,3% en zone urbaine, de 0,8% en zone semi-urbaine et de 0,1% en zone rurale.

Conclusion

La prévalence du virus de l’hépatite C est estimée à 8,2%. Elle est parmi les plus élevées en Afrique.

Abstract

Introduction

The national prevalence of hepatitis C virus (HCV) is not known in Burundi. Studies carried out in specific populations found various rates. There is no nationwide study made in the country.

Aim

To determine the prevalence of anti-HCV antibodies in Burundi based on a nationwide survey.

Methods

During a nationwide survey of HIV prevalence in 2002, conducted by the CEFORMI in CHU Kamenge, two to four ml of serum and plasma had been extracted from each sample and stored under −20°C for an ulterior use. We recuperated and analyzed them.

Results

A total of 5569 persons have been enrolled. 2660 (47,8%) were males and 2909 (52,2%) females. The mean age was 31±15 years with a median of 28 years. The global prevalence of HVC antibodies was 8,2%. It was 8,3% among males and 8,1% among females. According to strata, the prevalence was 10% in urban area, 9,1% in semi-urban area and 7,4% in rural area. The co-infection with HIV was 1,3% in urban area, 0,8% in semi-urban area and 0,1% in rural area.

Conclusion

The prevalence of anti-HCV antibodies is estimated to 8,2% in Burundi. It is one of the highest rates in Africa.

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Authors and Affiliations

  1. Département de médecine interne, Centre hospitalo-universitaire de Kamenge (CHUK), Bujumbura, Burundi

    R. Ntagirabiri, E. Baransaka, A. Ndayiragije & T. Niyongabo

Authors
  1. R. Ntagirabiri
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  2. E. Baransaka
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  3. A. Ndayiragije
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  4. T. Niyongabo
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Corresponding author

Correspondence to R. Ntagirabiri.

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Ntagirabiri, R., Baransaka, E., Ndayiragije, A. et al. Prévalence du virus de l’hépatite C au Burundi : enquête nationale. J Afr Hepato Gastroenterol 8, 25–28 (2014). https://doi.org/10.1007/s12157-014-0511-6

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  • DOI: https://doi.org/10.1007/s12157-014-0511-6

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