Calcifying Odontogenic Cyst Showing a Varied Epithelial Lining: An Additional Case with Implications for the Divergent Differentiation Capacity of the Cyst Epithelium
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To the Editors,
Argyris and Koutlas  have described a single cystic lesion of orthokeratinized odontogenic cyst (OOC) and odontogenic keratocyst (OKC) with focal ghost cell keratinization/calcification in a patient with Gardner syndrome. They speculated that two distinct types of keratinizing OCs occurred simultaneously as separate foci within the same lesion under the common molecular (Wnt/β-catenin) pathway, since examination of multiple sections revealed that at no point were the two cysts in continuity. This is an interesting contribution demonstrating the morphological diversity that OCs may show [2, 3, 4]. Here we add an unusual case of calcifying odontogenic cyst (COC) in which the unicystic epithelium combined areas resembling dentigerous cyst (DC), OOC and OKC, with a minor component of mucous cells and duct-like structures. The COC lining also showed occasional granular parakeratosis (GP).
The patient, a 33-year-old man, presented with a painless facial swelling. The left...
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Conflict of interest
The authors declare no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
Informed consent was obtained.
- 3.Pindborg JJ. Variations in odontogenic cyst epithelium. In: Husted E, Hjørting-Hansen E, editors. Oral surgery. Copenhagen: Munksgaard; 1967. pp. 120–7.Google Scholar
- 7.Geist J, Gordon S, Wesley R. Oral pathology quiz: an unusual pericoronal cyst. J Mich Dent Assoc. 2003;85:42–3.Google Scholar
- 21.Park JC, Cheung WS, Campbell KM. A rare case of gingival cyst in a child. J Dent Child. 2017;84:44–6.Google Scholar