Putting All the Pieces Together: Clinical, Macroscopic and Microscopic Characteristics of Subacute Thyroiditis

Sine qua non Clinicopathologic Correlation


Subacute thyroiditis (SAT) is a self-limiting inflammatory condition of the thyroid gland in which multinucleated giant cells constitute a key histological finding. SAT is generally a clinical diagnosis and consequently its histological features are rarely encountered by pathologist. Herein, we present a case that exemplifies the characteristic clinical and pathological features of this entity. In addition, we compare SAT to other thyroid disorders characterized by the presence of multinucleated giant cells.


Subacute thyroiditis Quervain’s thyroiditis Multinucleated giant cells Non-neoplastic lesions of the thyroid 


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyIcahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.Department of Anatomic PathologyMoffitt Cancer CenterTampaUSA

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