Putting All the Pieces Together: Clinical, Macroscopic and Microscopic Characteristics of Subacute Thyroiditis
Subacute thyroiditis (SAT) is a self-limiting inflammatory condition of the thyroid gland in which multinucleated giant cells constitute a key histological finding. SAT is generally a clinical diagnosis and consequently its histological features are rarely encountered by pathologist. Herein, we present a case that exemplifies the characteristic clinical and pathological features of this entity. In addition, we compare SAT to other thyroid disorders characterized by the presence of multinucleated giant cells.
KeywordsSubacute thyroiditis Quervain’s thyroiditis Multinucleated giant cells Non-neoplastic lesions of the thyroid
- 5.Wenig BM, Heffes CS, Adair CF. Nonautoimmune thyroiditides. In: Atlas of endocrine pathology. Philadelphia: W.B. Sauders Company; 1997. pp. 53–5.Google Scholar
- 6.Rosai J, DeLellis RA, Carcangiu ML, Frable WJ, Tallini G. Tumor-Like conditions of the thyroid gland tumors of the thyroid and parathyroid gland. 21. 4th ed. American Registry of Pathology; 2014. p. 342.Google Scholar
- 7.Wenig BM. Non-neoplastic diseases of the thyroid gland. In: Atlas of head and neck pathology. 3rd ed. Amsterdam: Elsevier; 2016. pp. 1240–3.Google Scholar
- 9.Elsheikh TM, Cochand-Priollet B, Hong SW, Benign SMK. In: Ali S, Cibas E, editors. The bethesda system for reporting thyroid cytopathology. 2nd ed. New York: Springer; 2018. pp. 39–40.Google Scholar
- 13.Sweeney LB, Stewart C, Gaitonde DY. Thyroiditis: an integrated approach. Am Family Phys. 2014;90(6):389 – 96.Google Scholar