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The Indian Journal of Pediatrics

, Volume 85, Issue 6, pp 413–414 | Cite as

Severe Dengue: Developing a Universally Applicable Simple Prediction Model

  • Sunit C. Singhi
EDITORIAL COMMENTARY
  • 84 Downloads

Globally dengue causes 50 million infections per year and an estimated 20,000 deaths annually, posing a large disease and economic burden. In 2009, World Health Organization (WHO) proposed a classification categorising the disease as dengue with or without warning signs and severe dengue, to enhance early recognition of severe dengue [1]. The 2009 classification suggests 7 clinical signs as warning signs for severe dengue based on a multicenter study in Southeast Asia and Latin American countries [2] and global expert consensus. WHO guidelines suggest that presence of any warning sign should lead to admission to a healthcare facility and intravenous fluid therapy [1]. A systematic review showed that sensitivity of 2009 classification to identify severe dengue ranged between 59 and 98% (88%/98%: prospective studies), and specificity between 41 and 99% (99%: prospective studies) [3]. Although the WHO 2009 guidelines’ system of early warning signs is easy to use and sensitive in...

Notes

Compliance with Ethical Standards

Conflict of Interest

None.

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Copyright information

© Dr. K C Chaudhuri Foundation 2018

Authors and Affiliations

  1. 1.Division of Pediatrics, Medanta, The MedicityGurugramIndia
  2. 2.Department of Pediatrics & Advanced Pediatrics CentrePost Graduate Institute of Medical Education and ResearchChandigarhIndia

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