Table 2 Immunohistochemical panel for diagnosis of the subtypes of ovarian cancer

From: SEOM clinical guideline in ovarian cancer (2020)

  Pax8 WT1 P53 ER NAPSA Ki67
HGSC  +   +   + (diffuse)  +  −/ +  High
LGSC  +   +   +  Low
CCC  +  −/ +   +  N/A
EC  +   +  −/ +  N/A
MC −/ +  −/ + (focal) N/A
  1. HGSC high-grade serous carcinoma, LGSC low-grade serous carcinoma, CCC clear cell carcinoma, EC endometrioid carcinoma, MC mucinous carcinoma, WT1 Wilms Tumour 1, ER estrogen receptor, NAPSA naspin A, N/A not applicable