Ossicular discontinuity is the most common cause of conductive hearing loss. The use of ossicular graft material in ossicular chain reconstruction significantly improves the result in hearing. This study was conducted to compare and analyze the outcome of ossicular reconstruction using allogenic septal spur cartilage and autologous cortical bone in terms of hearing results and graft uptake rates. Study design: randomized clinical trial. Study included 112 patients visiting our ENT department. Patients between 16 and 50 years of age with history of chronic ear discharge and air–bone–gap (ABG) of > 35 dB and ossicular involvement were included in the study. The patients underwent detailed ENT examination, audiological and radiological assessment of temporal bone and those patients with evidence of ossicular erosion were subjected to ossiculoplasty with allogenic septal spur cartilage (group I) and autologous cortical bone (group II) randomly. The patients were followed up to 6 months to analyze functional and anatomical results. 50 patients out of 56 patients (90%) from group I who underwent allogenic septal cartilage ossicular reconstruction showed significant improvement in hearing as assessed by pure tone audiogram after 3 months and 6 months. Remaining 10% of patients who did not show hearing improvement on PTA were reopened after 6 months. It was observed that the stapes head got necrosed in them. 40 patients (72%) out of 56 patients (50%) from group II who underwent autologous cortical bone reconstruction showed hearing improvement. Remaining 16 patients (28%) showed no hearing improvement. They were reopened and ankylosis, dislocation of ossicle and extrusion were noted. In our study, graft uptake rates, formation of retraction pockets, and hearing improvements were analyzed. Complications like ankylosis formation, dislocation of ossicle and extrusion rates were more in the group II compared to group I. Hearing results of group I are better compared to group II and the allogenic septal cartilage being readily available is a good option for ossicular reconstruction.
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We are thankful to Dr S.M Azeem Mohiyuddin Department of ENT and Head and Neck Surgery, Sri Devaraj Urs Medical College, Tamaka, Kolar for his helpful discussion and technical expertise. We express our gratitude to Dr. Sekhar for supporting me and constant encouragement and Dr Indhu Department of ENT and HNS, Sri Devraj Urs Medical College and Research Centre, Tamaka, Kolar helping in editing the article.
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Authors declare no conflict of interest
Taken from the Sridevaraj medical college ethical committee.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional committee, Institutional ethical committee approved it.
Approval for the study was obtained from the Institutional Ethics Committee. Informed consent was required for this study.
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Prasad, K.C., Koneru, P., Swapanthi, M.B. et al. Comparision of Allogenic Cartilage and Autologous Cortical Bone in Ossicular Reconstruction: A Comparative Study. Indian J Otolaryngol Head Neck Surg (2020). https://doi.org/10.1007/s12070-020-01924-8
- Allogenic septal spur cartilage
- Autologous cortical bone