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Genetics of language and its implications on language interventions

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Abstract

Genetic variation of language genes affect neurophysiology of brain and can thus influence the way people respond to environmental language input, leading to differences in terms of their response to environmental language learning. Conversely, language learning environment too can affect gene expressions through neuroepigenetic mechanisms, leading to increased interindividual differences. Further, language-related cognitive processes such as learning, working memory and perception; and language-related affective factors such as stress and positive emotion involve neuroplasticity, which is also epigenetically regulated. Language intervention methods must understand the extent and the type of difficulties, and must offer personalized learning and medical solutions. Medical intervention in terms of epigenetics and neurotransmitter regulation is proposed in addition to effective teaching methods to aid in effective language acquisition.

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References

  • Alarcón M., Abrahams B. S., Stone J. L., Duvall J. A., Perederiy J. V., Bomar J. M. et al. 2008 Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am. J. Hum. Genet. 82, 150–159.

    PubMed  PubMed Central  Google Scholar 

  • Allen N. D. 2008 Temporal and epigenetic regulation of neurodevelopmental plasticity. Philos. Trans. Biol. Sci. 363, 23–38.

    CAS  Google Scholar 

  • Amarillo I. E., Li W. L., Li X., Vilain E. and Kantarci S. 2014 De novo single exon deletion of AUTS2 in a patient with speech and language disorder: a review of disrupted AUTS2 and further evidence for its role in neurodevelopmental disorders. Am. J. Med. Genet. 164, 958–965.

    CAS  Google Scholar 

  • Andrzejewski M. E., Spencer R. C. and Kelley A. E. 2005 Instrumental learning, but not performance, requires dopamine D1-receptor activation in the amygdala. Neuroscience 135, 335–345.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Anyadubalu C. C., Atasheneh N., Izadi A. and Krashen S. D. 2010 The role of teachers in reducing/increasing listening comprehension test anxiety: a case of Iranian EFL learners. English Lang. Teach. 5, 193–198.

    Google Scholar 

  • Atasheneh N. and Izadi A. 2012 The role of teachers in reducing/increasing listening comprehension test anxiety: a case of Iranian EFL learners. English Lang. Teach. 5, 178–187.

    Google Scholar 

  • Bagot R. C. and Meaney M. J. 2010 Epigenetics and the biological basis of gene? environment interactions. J. Am. Acad. Child Adolesc. Psychiatry 49, 752–771.

    PubMed  Google Scholar 

  • Berwick R. C. and Chomsky N. 2016 Why only us: language and evolution. MIT Press, Cambridge, MS.

    Google Scholar 

  • Borrelli E., Nestler E. J., Allis C. D. and Sassone-Corsi P. 2008 Decoding the epigenetic language of neuronal plasticity. Neuron 60, 961–974.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Canli T., Ferri J. and Duman E. A. 2009 Genetics of emotion regulation. Neuroscience 164, 43–54.

    CAS  PubMed  Google Scholar 

  • Caspi A., Williams B., Kim-Cohen J., Craig I. W., Milne B. J., Poulton R. et al. 2007 Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc. Natl. Acad. Sci. USA 104, 18860–18865.

    CAS  PubMed  Google Scholar 

  • Caspi A., Hariri A. R., Andrew H., Uher R. and Moffitt T. E. 2010 Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am. J. Psychiatry Part A 167, 509–527.

    Google Scholar 

  • Chandrasekaran B., Yi H. G., Blanco N. J., McGeary J. E. and Maddox W. T. 2015 Enhanced procedural learning of speech sound categories in a genetic variant of FOXP2. J. Neurosci. 35, 7808–7812.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Chang H., Hoshina N., Zhang C., Ma Y., Cao H., Wang Y. et al. 2017 The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Mol. Psychiatry, 23, 400–412

    PubMed  PubMed Central  Google Scholar 

  • Chen X. S., Reader R. H., Hoischen A., Veltman J. A., Simpson N. H., Francks C. et al. 2017a Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment. Sci. Rep. 7, 1–17.

    Google Scholar 

  • Chen Y., Zhao H., Zhang Y. X. and Zuo P. X. 2017b DCDC2 gene polymorphisms are associated with developmental dyslexia in Chinese Uyghur children. Neural Regener. Res. 12, 259–266.

    Google Scholar 

  • Chomsky N. 2006 Language and mind, 3rd edition. Cambridge University Press, Cambridge.

    Google Scholar 

  • Cope N., Harold D., Hill G., Moskvina V., Stevenson J., Holmans P. et al. 2005 Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. Am. J. Hum. Genet. 76, 581–591.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Crespi B., Read S. and Hurd P. 2017 Segregating polymorphisms of FOXP2 are associated with measures of inner speech, speech fluency and strength of handedness in a healthy population. Brain Lang. 173, 33–40.

    PubMed  Google Scholar 

  • Day J. J. and Sweatt J. D. 2010 DNA methylation and memory formation. Nat. Neurosci. 13, 1319–1323.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Day J. J. and Sweatt J. D. 2011 Epigenetic mechanisms in cognition. Neuron 70, 813–829.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Deters K. D., Nho K., Risacher S. L., Kim S., Ramanan V. K., Crane P. K. et al. 2017 Genome-wide association study of language performance in Alzheimer’s disease. Brain Lang. 172, 22–29.

    PubMed  PubMed Central  Google Scholar 

  • Dolcos F., Iordan A. D. and Dolcos S. 2011 Neural correlates of emotion–cognition interactions: a review of evidence from brain imaging investigations. J. Cognit. Psychol. 23, 669–694.

    Google Scholar 

  • Dzafic I., Burianova H., Periyasamy S. and Mowry B. 2018 Association between schizophrenia polygenic risk and neural correlates of emotion perception. Psychiatry Res.: Neuroimaging 276, 33–40.

    PubMed  Google Scholar 

  • Estruch S. B., Graham S. A., Chinnappa S. M., Deriziotis P. and Fisher S. E. 2016 Functional characterization of rare FOXP2 variants in neurodevelopmental disorder. J. Neurodev Disord. 8, 44.

    PubMed  PubMed Central  Google Scholar 

  • Fass D. M., Schroeder F. A., Perlis R. H. and Haggarty S. J. 2014 Epigenetic mechanisms in mood disorders: targeting neuroplasticity. Neuroscience 264, 112–130.

    CAS  PubMed  Google Scholar 

  • Felling R. J. and Song H. 2015 Epigenetic mechanisms of neuroplasticity and the implications for stroke recovery. Exp. Neurol. 268, 37–45.

    CAS  PubMed  Google Scholar 

  • Filges I., Shimojima K., Okamoto N., Röthlisberger B., Weber P., Huber A. R. et al. 2011 Reduced expression by SETBP1 haploinsufficiency causes developmental and expressive language delay indicating a phenotype distinct from Schinzel-Giedion syndrome. J. Med. Genet. 48, 117–122.

    CAS  PubMed  Google Scholar 

  • Fisher S. E. and Scharff C. 2009 FOXP2 as a molecular window into speech and language. Trends Genet. 25, 166–177.

    CAS  PubMed  Google Scholar 

  • Fried I., Wilson C. L., Morrow J. W., Cameron K. A., Behnke E. D., Ackerson L. C. and Maidment N. T. 2001 Increased dopamine release in the human amygdala during performance of cognitive tasks. Nat. Neurosci. 4, 201–206.

    CAS  PubMed  Google Scholar 

  • Gialluisi A., Newbury D. F., Wilcutt E. G., Consortium T. S. L. I. and Luciano M. 2014 Genome-wide screening for DNA variants associated with reading and language traits. Genes Brain Behav. 13, 686–701.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Golestani N. and Zatorre R. J. 2009 Individual differences in the acquisition of second language phonology. Brain Lang. 109, 55–67.

    PubMed  Google Scholar 

  • Gräff J. and Mansuy I. M. 2008 Epigenetic codes in cognition and behaviour. Behav. Brain Res. 192, 70–87.

    PubMed  Google Scholar 

  • Gray J. A. 1990 Brain systems that mediate both emotion and cognition. Cognit. Emotion 4, 269–288.

    Google Scholar 

  • Hannula-Jouppi K., Kaminen-Ahola N., Taipale M., Eklund R., Nopola-Hemmi J., Kääriäinen H. and Kere J. 2005 The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. PLoS Genet. 1, 0467–0474.

    CAS  Google Scholar 

  • Hauser M. D., Chomsky N. and Fitch W. T. S. 2002 The faculty of language: what is it, who has it, and how did it evolve? Science 298, 1569–1579.

    CAS  PubMed  Google Scholar 

  • Hippolyte L., Maillard A. M., Rodriguez-Herreros B., Pain A., Martin-Brevet S., Ferrari C. et al. 2016 The number of genomic copies at the 16p11.2 locus modulates language, verbal memory and inhibition. Biol. Psychiatry 80, 129–139.

    CAS  PubMed  Google Scholar 

  • Isgett S. F., Algoe S. B., Boulton A. J., Way B. M. and Fredrickson B. L. 2016 Common variant in OXTR predicts growth in positive emotions from loving-kindness training. Psychoneuroendocrinology 73, 244–251.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Jennifer J. M. and Ponniah R. J. 2017 Investigating the levels, types and causes of second language writing anxiety among Indian freshmen. J. Asia TEFL 14, 557–563.

    Google Scholar 

  • Jennifer J. M. and Ponniah J. R. 2018 Acquisition of writing by reading and its impact on cognition. In The idea and practice of reading (ed. R. J. Ponniah and S. Venkatesan), pp. 41–56. Springer, Singapore.

    Google Scholar 

  • Keifer J. 2017 Primetime for learning genes. Genes 8, 69.

    PubMed Central  Google Scholar 

  • Kennedy A. J., Rahn E. J., Paulukaitis B. S., Michael T. P., Day J. J., David J. et al. 2016 Tcf4 regulates synaptic plasticity, DNA methylation and memory function. Cell Rep. 16, 2666–2685.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Kitayama S., King A., Hsu M., Liberzon I. and Yoon C. 2016 Dopamine-system genes and cultural acquisition: the norm sensitivity hypothesis. Curr. Opin. Psychol. 8, 167–174.

    PubMed  Google Scholar 

  • Knowles E. E. M., Mathias S. R., McKay D. R., Sprooten E., Blangero J., Almasy L. and Glahn D. C. 2014 Genome-wide analyses of working-memory ability: a review. Curr. Behav. Neurosci. Rep. 1, 224–233.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Krashen S. D. 1982 Principles and practice in second language acquisition, 1st edition. Pergamon Press Inc., Oxford.

    Google Scholar 

  • Ladd D., Dediu D. and Kinsella A. 2008 Languages and genes: reflections on biolinguistics and the nature-nurture question. Biolinguistics 2, 114–126. Retrieved from http://www.biolinguistics.eu/index.php/biolinguistics/article/view/39/61.

  • Laffin J. J. S., Raca G., Jackson C. A., Strand E. A., Jakielski K. J. and Shriberg L. D. 2012 Novel candidate genes and regions for childhood apraxia of speech (CAS) identified by array comparative genomic hybridization. Genet. Med. 14, 928–936.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Lai C. S. L., Fisher S. E., Hurst J. A. and Vargha-khadem F. 2001 A forkhead-domain gene is mutated in a severe speech and language disorder. Nature 413, 519–523.

    CAS  PubMed  Google Scholar 

  • Lesca G., Rudolf G., Bruneau N., Lozovaya N., Labalme A., Boutry-Kryza N. et al. 2013 GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction. Nat. Genet. 45, 1061–1066.

    CAS  PubMed  Google Scholar 

  • Levenson J. and Sweatt J. 2005 Epigenetic mechanisms in memory formation. Nat. Rev. Neurosci. 6, 108–118.

    CAS  PubMed  Google Scholar 

  • Levinson S. C. 2012 The original sin of cognitive science. Top. Cognit. Sci. 4, 396–403.

    Google Scholar 

  • Liu K. X., Edwards B., Lee S., Finelli M. J., Davies B., Davies K. E. and Oliver P. L. 2015 Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis. Brain 138, 1167–1181.

    PubMed  PubMed Central  Google Scholar 

  • Mc Ewen B. 2015 Epigenetics and learning. Trends Neurosci. Educ. 4, 108–111.

    Google Scholar 

  • McEwen B. S. 2016 In pursuit of resilience: stress, epigenetics, and brain plasticity. Ann. N Y Acad. Sci. 1373, 56–64.

    PubMed  Google Scholar 

  • McEwen B. S., Eiland L., Hunter R. G. and Miller M. M. 2012 Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress. Neuropharmacology 62, 3–12.

    CAS  PubMed  Google Scholar 

  • McNamara P. and Durso R. 2018 The dopamine system, Parkinson’s disease and language function. Curr. Opin. Behav. Sci. 21, 1–5.

    Google Scholar 

  • Méndez López M. G. and Fabela Cárdenas M. A. 2014 Emotions and their effects in a language learning Mexican context. System 42, 298–307.

    Google Scholar 

  • Meng H., Smith S. D., Hager K., Held M., Liu J., Olson R. K. et al. 2005 DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc. Natl. Acad. Sci. USA 102, 17053–17058.

    CAS  PubMed  Google Scholar 

  • Mondal P. 2016 Language and cognitive structures of emotion. Palgrave Macmillan.

  • Morgan A. T., Mei C., Da Costa A., Fifer J., Lederer D., Benoit V. et al. 2015a Speech and language in a genotyped cohort of individuals with Kabuki syndrome. Am. J. Med. Genet. Part A 167, 1483–1492.

    CAS  PubMed  Google Scholar 

  • Morgan T. J. H., Uomini N. T., Rendell L. E., Chouinard-Thuly L., Street S. E., Lewis H. M. et al. 2015b Experimental evidence for the co-evolution of hominin tool-making teaching and language. Nat. Commun. 6, 1–8.

    Google Scholar 

  • Moya C. and Henrich J. 2016 Culture-gene coevolutionary psychology: cultural learning, language, and ethnic psychology. Curr. Opin. Psychol. 8, 112–118.

    PubMed  Google Scholar 

  • Mozzi A., Riva V., Forni D., Sironi M., Marino C., Molteni M. et al. 2017 A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: evidence from two Italian independent samples. Am. J. Med. Genet. Part B 174, 578–586.

    CAS  Google Scholar 

  • Newbury D. F., Winchester L., Addis L., Paracchini S., Buckingham L. L., Clark A. et al. 2009 CMIP and ATP2C2 modulate phonological short-term memory in language impairment. Am. J. Hum. Genet. 85, 264–272.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Ni H. 2012 The effects of affective factors in SLA and pedagogical implications. Theory Pract. Lang. Stud. 2, 1508–1513.

    Google Scholar 

  • Nieto S. J., Patriquin M. A., Nielsen D. A. and Kosten T. A. 2016 Don’t worry; be informed about the epigenetics of anxiety. Pharmacol. Biochem. Behav. 146–147, 60–72.

    PubMed  PubMed Central  Google Scholar 

  • Ocklenburg S., Arning L., Hahn C., Gerding W. M., Epplen J. T., Güntürkün O. and Beste C. 2011 Variation in the NMDA receptor 2B subunit gene GRIN2B is associated with differential language lateralization. Behav. Brain Res. 225, 284–289.

    CAS  PubMed  Google Scholar 

  • Ölmez F. 2015 An investigation into the relationship between L2 reading motivation and reading achievement. Procedia – Soc. Behav. Sci. 199, 597–603.

    Google Scholar 

  • Owens S. F., Picchioni M. M., Rijsdijk F. V., Stahl D., Vassos E., Rodger A. K. et al. 2011 Genetic overlap between episodic memory deficits and schizophrenia: results from the Maudsley Twin Study. Psychol. Med. 41, 521–532.

    CAS  PubMed  Google Scholar 

  • Pessoa L. 2008 On the relationship between emotion and cognition. Nat. Rev. Neurosci. 9, 148–158.

    CAS  PubMed  Google Scholar 

  • Peter C. J., Fischer L. K., Kundakovic M., Garg P., Jakovcevski M., Dincer A. et al. 2016 DNA Methylation signatures of early childhood malnutrition associated with impairments in attention and cognition. Biol. Psychiatry 80, 765–774.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Pinker S. 2007 The language instinct, 3rd edition. William Moorw and Company, New York.

    Google Scholar 

  • Ponniah R. J. 2009 The role of grammar: an insight into the skill-building and the output hypotheses. Mod. J. Appl. Linguist. 1, 275–285.

    Google Scholar 

  • Ponniah R. J. 2011 Incidental acquisition of vocabulary by reading. Read Matrix 11, 135–139.

    Google Scholar 

  • Reich P. A. and Richards B. A. 2004 Epigenetics and language: the minimalist program, connectionism, and biology. Linguist. Atl. 25, 7–21.

    Google Scholar 

  • Rendall A. R., Tarkar A., Contreras-Mora H. M., LoTurco J. J. and Fitch R. H. 2017 Deficits in learning and memory in mice with a mutation of the candidate dyslexia susceptibility gene Dyx1c1. Brain Lang. 172, 30–38.

    PubMed  Google Scholar 

  • Roll P., Vernes S. C., Bruneau N., Cillario J., Ponsole-Lenfant M., Massacrier A. et al. 2010 Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex. Hum. Mol. Genet. 19, 4848–4860.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Satterlee J. S., Beckel-Mitchener A., Little R. A., Procaccini D., Rutter J. L. and Lossie A. C. 2015 Neuroepigenomics: resources, obstacles, and opportunities. Neuroepigenetics 1, 2–13.

    PubMed  PubMed Central  Google Scholar 

  • Scerri T. S., Darki F., Newbury D. F., Whitehouse A. J. O., Peyrard-Janvid M., Matsson H. et al. 2012 The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure. PLoS One 7, e50321.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Scheidegger M., Henning A., Walter M., Boeker H., Weigand A., Seifritz E. and Grimm S. 2016 Effects of ketamine on cognition-emotion interaction in the brain. NeuroImage. 124 (Pt A), 8–15.

  • Schulze K., Vargha-Khadem F. and Mishkin M. 2018 Phonological working memory and FOXP2. Neuropsychologia 108, 147–152.

    PubMed  Google Scholar 

  • Scult M. A. and Hariri A. R. 2018 A brief introduction to the neurogenetics of cognition-emotion interactions. Curr. Opin. Behav. Sci. 19, 50–54.

    PubMed  Google Scholar 

  • Sniekers S., Stringer S., Watanabe K., Jansen P. R., Coleman J. R. I., Krapohl E. et al. 2017 Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nat. Genet. 49, 1107–1112.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Sriganesh R., Rahul D. R. and Ponniah R. J. 2018 Genetics of reading ability and its role in solving reading difficulties. In The idea and practice of reading (ed. R. J. Ponniah and S. Venkatesan), pp. 125–139. Springer, Singapore.

    Google Scholar 

  • Sterelny K. 2012 Language, gesture, skill: the co-evolutionary foundations of language. Philos. Trans. R. Soc. B: Biol. Sci. 367, 2141–2151.

    Google Scholar 

  • Taipale M., Kaminen N., Nopola-Hemmi J., Haltia T., Myllyluoma B., Lyytinen H. et al. 2003 A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proc. Natl. Acad. Sci. USA 100, 11553–11558.

    CAS  PubMed  Google Scholar 

  • Telese F., Gamliel A., Skowronska-Krawczyk D., Garcia-Bassets I. and Rosenfeld M. G. 2013 Seq-ing insights into the epigenetics of neuronal gene regulation. Neuron 77, 606–623.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Thevenon J., Callier P., Andrieux J., Delobel B., David A., Sukno S. et al. 2013 12p13.33 microdeletion including ELKS/ERC1, a new locus associated with childhood apraxia of speech. Eur. J. Hum. Genet. 21, 82–88.

    CAS  PubMed  Google Scholar 

  • Toyokawa S., Uddin M., Koenen K. C. and Galea S. 2012 How does the social environment ‘get into the mind’? Epigenetics at the intersection of social and psychiatric epidemiology. Soc. Sci. Med. 74, 67–74.

    PubMed  Google Scholar 

  • Tran C., Wigg K. G., Zhang K., Cate-Carter T. D., Kerr E., Field L. L. et al. 2014 Association of the ROBO1 gene with reading disabilities in a family-based analysis. Genes, Brain Behav. 13, 430–438.

    CAS  Google Scholar 

  • Turner S. J., Hildebrand M. S., Block S., Damiano J., Fahey M., Reilly S. et al. 2013 Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria. Am. J. Med. Genet. Part A 161, 2321–2326.

    CAS  Google Scholar 

  • Vernes S. C., Newbury D. F., Abrahams B. S., Winchester L., Nicod J., Groszer M. et al. 2008 A functional genetic link between distinct developmental language disorders. N. Engl. J. Med. 359, 2337–2345.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Villanueva P., Nudel R., Hoischen A., Fernández M. A., Simpson N. H., Gilissen C. et al. 2015 Exome sequencing in an admixed isolated population indicates NFXL1 variants confer a risk for specific language impairment. PLoS Genet. 11, e1004925.

    PubMed  PubMed Central  Google Scholar 

  • Wang X., Hui Z., Dai X., Terry P. D., Zhang Y., Ma M. et al. 2017 Micronutrient-fortified milk and academic performance among Chinese middle school students: a cluster-randomized controlled trial. Nutrients 9, 226.

    PubMed Central  Google Scholar 

  • Williams L. M., Tsang T. W., Clarke S. and Kohn M. 2010 An “integrative neuroscience” perspective on ADHD: linking cognition, emotion, brain and genetic measures with implications for clinical support. Expert Rev. Neurother. 10, 1607–1621.

    PubMed  Google Scholar 

  • Wingo A. P., Almli L. M., Stevens J. S., Jovanovic T., Wingo T. S., Tharp G. et al. 2017 Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs. Mol. Psychiatry 22, 774–783.

    CAS  PubMed  Google Scholar 

  • Wong P. C. M. and Ettlinger M. 2011 Predictors of spoken language learning. J. Commun. Disord. 44, 564–567.

    PubMed  PubMed Central  Google Scholar 

  • Worthey E. A., Raca G., Laffin J. J., Wilk B. M., Harris J. M., Jakielski K. J. et al. 2013 Whole-exome sequencing supports genetic heterogeneity in childhood apraxia of speech. J. Neurodev. Disord. 5, 29.

    PubMed  PubMed Central  Google Scholar 

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  1. National Institute of Technology Tiruchirappalli, Tiruchirappalli, 620 015, India

    Radhakrishnan Sriganesh & R. Joseph Ponniah

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Sriganesh, R., Ponniah, R.J. Genetics of language and its implications on language interventions. J Genet 97, 1485–1491 (2018). https://doi.org/10.1007/s12041-018-1006-9

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