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Association of MITF gene with hearing and pigmentation phenotype in Hedlund white American mink (Neovison vison)

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References

  • Anistoroaei R., Fredholm M., Christensen K., and Leeb T. 2008 Albinism in the American mink (Neovison vison) is associated with a tyrosinase nonsense mutation. Anim. Genet. 39, 645–648.

    Article  CAS  PubMed  Google Scholar 

  • Anistoroaei R., ten Hallers B., Nefedov M., Christensen K. and de Jong P. 2011 Construction of an American mink bacterial artificial chromosome (BAC) library and sequencing candidate genes important for the fur industry. BMC Genomics 12, 35.

  • Breathnach A. S. 1988 Extra-cutaneous melanin. Pigm. Cell Res. 1(4), 234–237.

  • Conlee J.W., Parks Y. N., Schwartz I. R. and Creel D. J. 1989 Comparative anatomy of melanin pigment in the stria vascularis. Evidence for distinction between melanocytes and intermediate cells in the cat. Acta Otolaryngol. 107, 48–58.

  • Graw J., Pretsch W. and Löster J. 2003 Mutation in intron 6 of the hamster Mitf gene leads to skipping of the subsequent exon and creates a novel animal model for the human Waardenburg syndrome type II. Genetics 164, 1035–1041.

  • Hallsson J. H, Haflidadóttir B. S., Schepsky A., Arnheiter H. and Steingrímsson E. 2007 Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains. Pigment Cell Res. 20, 185–200.

  • Hauswirth R., Haase B., Blatter M., Brook S. A., Burger D., Drögemüller D. et al. 2012 Mutations in MITF and PAX3 cause ‘splashed white’ and other white spotting phenotypes in horses. PLoS Genet. 8, e1002653.

  • Hibino H., Nin F., Tsuzuki C., and Kurachi Y. 2010 How is the highly positive endocochlear potential formed? The specific architecture of the stria vascularis and the role of the ion-transport apparatus. Eur. J. Physiol. 459, 521–533.

    Article  CAS  Google Scholar 

  • Karlsson E. K., Baranowska I.,Wade C.M., Salmon Hillberg N. H., Zody M. C., Anderson N. et al. 2007 Efficient mapping of Mendelian traits in dogs through genome-wide association. Nat. Genet. 39, 1321–1328.

  • Motohashi H., Hozawa K., Oshima T., Takeuchi T. and Takasaka T. 1994 Dysgenesis of melanocytes and cochlear dysfunction in mutant micropthalmia (mi) mice. Hear. Res. 80, 10–20.

  • Philipp U., Lupp B., Mömke S., Stein V., Tipold A., Eule J. C., Rehage J. and Distl O. 2011 A MITF mutation associated with a dominant white phenotype and bilateral deafness in German Fleckvieh cattle. PLoS One 6, e28857.

  • Steel P. K. and Barkway C. 1989 Another role for melanocytes: their importance for normal stria vascularis development in the mammalian inner ear. Development 107, 453–463.

    CAS  PubMed  Google Scholar 

  • Steingrimsson E., Copeland N. G., and Jenkins N. A. 2004 Melanocytes and the microphthalmia transcription factor network. Ann. Rev. Genet. 38, 365–411.

    Article  CAS  PubMed  Google Scholar 

  • Stevens A. 1982 Pigments and minerals. In theory and practice of histological techniques (ed. J. D. Bancroft and A. Stevens), pp. 242–266. Churchill Livingston, Edinburgh, Scotland.

  • Stritzel S., Wöhlke A., and Distl O. 2009 A role of the microphthalmia-associated transcription factor in congenital sensorineural deafness and eye pigmentation in Dalmatian dogs. J. Anim. Breed. Genet. 126 1, 59–62.

    Article  CAS  PubMed  Google Scholar 

  • Tachibana M. 2001 Cochlear melanocytes and MITF signaling. J. Investig. Dermatol. Symp. Proc. 6, 95–98.

  • Tachibana M., Takeda K., Nobukuni Y., Urabe K., Long J. E. et al. 1996 Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocytes characteristics. Nat. Genet. 14, 50–54.

  • Tachibana M., Takeda K., Nobukuni, et al. 1996 Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocytes characteristics. Nat. Genet. 14, 50–54.

    Article  CAS  PubMed  Google Scholar 

  • Walsh P. S., Metzger D. A., and Higuchi R. 1991 Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 10, 506–513.

    CAS  PubMed  Google Scholar 

  • Wright C. G. and Lee D. H. 1989 Pigmented cells of the stria vascularis and spiral ligament of the chinchilla. Acta Otolaryngol. 108, 190–200.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

This work was supported by Razvan Anistoroaei’s postdoctoral grant from the Danish Research Council (#27820) and funding from the Danish Fur Breeders Association. We are thankful to C.A. Halberg, M. Jakobsen and A. Strandsby for the technical assistance.

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Authors and Affiliations

  1. Department of Biology, Plant Growth and Development, University of Antwerp, 2020, Antwerp, Belgium

    MARIOS N. MARKAKIS

  2. Section of Anatomy and Biochemistry, University of Copenhagen, 1870, Frederiksberg C, Denmark

    VIBEKE E. SOEDRING & VIBEKE DANTZER

  3. Section of Genetics, Bioinformatics and Systems Biology, Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, 1870, Frederiksberg C, Denmark

    KNUD CHRISTENSEN & RAZVAN ANISTOROAEI

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  1. MARIOS N. MARKAKIS
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  2. VIBEKE E. SOEDRING
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  3. VIBEKE DANTZER
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  4. KNUD CHRISTENSEN
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  5. RAZVAN ANISTOROAEI
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Correspondence to RAZVAN ANISTOROAEI.

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MarkakisM. N., Soedring V. E.,Dantzer V., Christensen K. and Anistoroaei R. 2014 Association of MITF gene with hearing and pigmentation phenotype in Hedlund white American mink (Neovison vison). J. Genet. 93, xx–xx

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MARKAKIS, M.N., SOEDRING, V.E., DANTZER, V. et al. Association of MITF gene with hearing and pigmentation phenotype in Hedlund white American mink (Neovison vison). J Genet 93, 477–481 (2014). https://doi.org/10.1007/s12041-014-0370-3

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