Gold-catalyzed formation of substituted aminobenzophenone derivatives via intramolecular 6-endo-dig cyclization

Abstract

An efficient and straightforward synthetic method to access substituted aminobenzophenones has been developed. This transformation was catalyzed by gold and a new C—C bond was formed through intramolecular 6-endo-dig cyclization. The substituted aminobenzophenones were obtained in good to excellent yields.

Graphic abstract

Gold-catalyzed formation of substituted aminobenzophenone derivatives via intramolecular 6-endo-dig cyclization

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Figure 1
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Acknowledgements

D. P. thanks UGC for his senior research fellowship and AcSIR. We thank Director CSIR-IICT for his support. V. N. D. and Dr. K. S. thank the Central University of Karnataka.

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Correspondence to Suneel Kanaparthy.

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Dedicated to Doma Gowthami on the occasion of her birthday.

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Dalovai, P., Karunakar, G.V., Damodaran Nadar, V. et al. Gold-catalyzed formation of substituted aminobenzophenone derivatives via intramolecular 6-endo-dig cyclization. J Chem Sci 133, 19 (2021). https://doi.org/10.1007/s12039-020-01860-8

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Keywords

  • Aminobenzophenones
  • Cascade reaction
  • Gold catalysis
  • 6-endo-dig cyclization