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Niobium pentoxide, a recyclable heterogeneous solid surface catalyst for the synthesis of α-amino phosphonates

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Abstract

Niobium pentoxide, a bifunctional solid surface catalyst, has been successfully employed to facilitate the three-component reaction between aldehydes, amines and triethyl phosphite at room temperature under solvent-free conditions to generate α-amino phosphonate in moderate to good yields. The catalyst can be recycled through simple filtration and reused to effect this transformation.

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Acknowledgements

We thank the SERB, New Delhi for financial (Grant No. CRG/2019/002,960) support. AS acknowledges the UGC for the fellowship. We thank UGC-SAP, Department of Chemistry. We gratefully acknowledge the Department of Chemistry, Pondicherry University for HRMS facility (DST-FIST Sponsored); Central Instrumentation Facility, Pondicherry University for NMR and IR data.

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Authors and Affiliations

  1. Department of Chemistry, Pondicherry University, Puducherry, 605 014, India

    Anita Sahani, Ramana Sreenivasa Rao, Adithya Vadakkayil, Murugesan Santhosh, Mahalingam Mummoorthi, Muthupandi Karthick & Chinnasamy Ramaraj Ramanathan

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  1. Anita Sahani
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  2. Ramana Sreenivasa Rao
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  3. Adithya Vadakkayil
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  7. Chinnasamy Ramaraj Ramanathan
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Correspondence to Chinnasamy Ramaraj Ramanathan.

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Sahani, A., Rao, R.S., Vadakkayil, A. et al. Niobium pentoxide, a recyclable heterogeneous solid surface catalyst for the synthesis of α-amino phosphonates. J Chem Sci 133, 4 (2021). https://doi.org/10.1007/s12039-020-01853-7

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