Clear Cell Sarcoma of Sigmoid Colon: a Rare Malignancy with Common Clinical Manifestations

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References

  1. 1.

    Wang J, Thway K. Clear cell sarcoma-like tumor of the gastrointestinal tract: an evolving entity. Arch Pathol Lab Med. 2015;139:407–12.

    Article  Google Scholar 

  2. 2.

    Panagopoulos I, Mertens F, Isaksson M, Mandahl N. Absence of mutations of the BRAF gene in malignant melanoma of soft parts (clear cell sarcoma of tendons and aponeuroses). Cancer Genet Cytogenet. 2005;156:74–6.

    CAS  Article  Google Scholar 

  3. 3.

    Zambrano E, Reyes-Mugica M, Franchi A, Rosai J. An osteoclast-rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: reports of 6 cases of a GIST simulator. Int J Surg Pathol. 2003 Apr;11(2):75–81.

    Article  Google Scholar 

  4. 4.

    Huang W, Zhang X, Li D, Chen J, Meng K, Wang Y, et al. Osteoclast-rich tumor of the gastrointestinal tract with features resembling those of clear cell sarcoma of soft parts. Virchows Arch. 2006;448(2):200–3.

    Article  Google Scholar 

  5. 5.

    Gahanbani Ardakani A, Boyle DJ, Elton C. Gastrointestinal clear cell sarcoma-like tumour of the ascending colon. Ann R Coll Surg Engl. 2016;98:e37.

    CAS  Article  Google Scholar 

  6. 6.

    Thway K, Fisher C. Tumours with EWSR1-CREB1 and EWSR1-ATF1 fusions: the current status. Am J Surg Pathol. 2012;36:e1–e11.

    Article  Google Scholar 

  7. 7.

    Thway K, Judson I, Fisher C. Clear cell sarcoma-like tumor of the gastrointestinal tract, presenting as a second malignancy after childhood hepatoblastoma. Case Rep Med. 2014;2014:984369.

    Article  Google Scholar 

  8. 8.

    Balkaransingh P, Saad SA, Govil SC, Thind PK, Ballance CM, Weiss AR. Clear cell sarcoma of the gastrointestinal tract presenting as a second malignant neoplasm following neuroblastoma in infancy. Pediatr Blood Cancer. 2012;58(3):481–2.

    Article  Google Scholar 

  9. 9.

    Covinsky M, Gong S, Rajaram V, Perry A, Pfeifer J. EWS-ATF1 fusion transcripts in gastrointestinal tumors previously diagnosed as malignant melanoma. Hum Pathol. 2005;36(1):74–81.

    CAS  Article  Google Scholar 

  10. 10.

    Moslim MA, Falk GA, Cruise M, Morris-Stiff G. Simultaneous clear cell sarcomas of the duodenum and jejunum. Case Rep Med. 2016;2016:1–5.

    Article  Google Scholar 

  11. 11.

    Stockman DL, Miettinen M, Suster S, Spagnolo D, Dominguez-Malagon H, Hornick JL, et al. Malignant gastrointestinal neuroectodermal tumor: clinicopathologic, immunohistochemical, ultrastructural, and molecular analysis of 16 cases with a reappraisal of clear cell sarcoma-like tumors of the gastrointestinal tract. Am J Surg Pathol. 2012;36(6):857–68.

    Article  Google Scholar 

  12. 12.

    Raskin GA, Pozharisski KM, Iyevleva AG, Rikov IV, Orlova RV, Imyanitov EN, et al. Unusual clinical presentation of gastrointestinal clear cell sarcoma. Gastrointest Tumors. 2015;2:83–8.

    CAS  Article  Google Scholar 

Download references

Acknowledgments

We are extremely thankful to Dr. Mohit Kumar, PhD, Cytogenetics, for providing the translocation study microphotograph.

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Correspondence to Navin Kumar.

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Kumar, N., Bhoriwal, S., Yadav, R. et al. Clear Cell Sarcoma of Sigmoid Colon: a Rare Malignancy with Common Clinical Manifestations. J Gastrointest Canc 51, 1070–1073 (2020). https://doi.org/10.1007/s12029-020-00413-z

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