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Hepatocellular Carcinoma in Paediatric Patients with Alagille Syndrome: Case Series and Review of Literature

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Fig. 1

Abbreviations

AFP:

Alfa-feto protein

AGS:

Alagille syndrome

CLD:

Chronic liver disease

HCC:

Hepatocellular carcinoma

LT:

Liver transplantation

TACE:

Transcatheter arterial chemoembolization

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Authors and Affiliations

  1. Institute of Liver Disease and Transplantation, Dr. Rela Institute & Medical Centre, Bharat Institute of Higher Education and Research, Chennai, India

    Joseph J. Valamparampil, Naresh Shanmugam, Mukul Vij, Mettu Srinivas Reddy & Mohamed Rela

  2. Kings College Hospital, London, UK

    Mohamed Rela

Authors
  1. Joseph J. Valamparampil
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  2. Naresh Shanmugam
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  3. Mukul Vij
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  4. Mettu Srinivas Reddy
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  5. Mohamed Rela
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Corresponding author

Correspondence to Joseph J. Valamparampil.

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Fig. 2A Well differentiated hepatocellular carcinoma with pale eosinophilic cytoplasm and sclerosis. 2B Glypican 3 immunopositivity in the tumor. 2C CK7 immunostaining highlighting the loss of interlobular bile ducts in explant liver. 2D Masson trichrome demonstrating cirrhosis in the explant liver (PNG 1551 kb)

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Valamparampil, J.J., Shanmugam, N., Vij, M. et al. Hepatocellular Carcinoma in Paediatric Patients with Alagille Syndrome: Case Series and Review of Literature. J Gastrointest Canc 51, 1047–1052 (2020). https://doi.org/10.1007/s12029-020-00391-2

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  • DOI: https://doi.org/10.1007/s12029-020-00391-2

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