Treatment of Colorectal Cancer: a Multidisciplinary Approach
- 48 Downloads
Colorectal cancer is the third most prevalent cancer in the world, preceded by prostate and lung cancers in men (10%) and breast and lung cancers in women (9.4%). Colorectal cancer is the fourth leading cause of death in men (7.6%) and the third in women (8.6%). A multidisciplinary approach has radically changed the way we deal with this disease among all specialist fields.
In this study, we propose comparing the multidisciplinary experience group (started in 2012) of S. Anna Hospital (University of Ferrara) with the previous approach to rectal cancer before the advent of the multidisciplinary program.
We find that more study depth of neoplastic disease as well as of each individual patient leads to more accurate staging and to a weighted therapy based on the needs of the individual. All the studies were performed in accordance with the guidelines established by the European and Italian associations.
KeywordsColorectal cancer Multidisciplinary group Laparoscopic surgery
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflicts of interest.
- 2.Valentini V, Aristei C, Glimelius B, Minsky BD, Beets-Tan R, Borras JM, et al. Multidisciplinary rectal cancer management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2). Radiother Oncol: J Eur Soc Ther Radiol Oncol. 92(2, August 2009):148–63. https://doi.org/10.1016/j.radonc.2009.06.027.
- 4.Loria FS, Iseas S, O’Connor JM, Pairola A, Chacon M, Mendez G, et al. Non-surgical management (NSM) of rectal cancer. series of 68 cases, long follow up in two leading centres in Argentina. Digestive and Liver Disease. June 1, 2016;0(0) https://doi.org/10.1016/j.dld.2016.05.012.
- 6.Bipat S, Glas AS, Slors FJM, Zwinderman AH, Bossuyt PMM, Stoker J. Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging—a meta-analysis. Radiology. September 2004;232(3):773–83. https://doi.org/10.1148/radiol.2323031368.CrossRefPubMedGoogle Scholar
- 8.Fiorica F, Trovò M, Anania G, Marcello D, Di Benedetto F, Marzola M, D’Acapito F, Nasti G, Berretta M. Is It Possible a Conservative Approach After Radiochemotherapy in Locally Advanced Rectal Cancer (LARC)? A Systematic Review of the Literature and Meta-analysis J Gastrointest Cancer. 2017. https://doi.org/10.1007/s12029-017-0041-8.
- 10.Kontovounisios C, Tan E, Pawa N, Brown G, Tait D, Cunningham D, Rasheed S, Tekkis P, “Selection process can improve the outcome in locally advanced and recurrent colorectal cancer: activity and results of a dedicated multidisciplinary colorectal cancer centre” Colorecatl dis, 2016 Sep 15.Google Scholar
- 11.Tomasone JR, Brouwers MC, Vukmirovic M, Grunfeld E, O'Brien MA, Urquhart R, Walker M, Webster F, Fitch M. “Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review” ESMO Open 2016;1:e000077. https://doi.org/10.1136/esmoopen-2016-000077.
- 12.You YN, Baxter NN, Stewart A, Nelson H. Is the increasing rate of local excision for stage I rectal cancer in the united states justified?: a nationwide cohort study from the National Cancer Database. Ann Surg. May 2007;245(5):726–33. https://doi.org/10.1097/01.sla.0000252590.95116.4f.CrossRefPubMedPubMedCentralGoogle Scholar
- 15.Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC Trial): multicentre, randomised controlled trial. Lancet (London, England). May 14, 2005;365(9472):1718–26. https://doi.org/10.1016/S0140-6736(05)66545-2.CrossRefGoogle Scholar
- 16.Lacy AM, García-Valdecasas JC, Delgado S, Castells A, Taurá P, Piqué JM, et al. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet (London, England). June 29, 2002;359(9325):2224–9. https://doi.org/10.1016/S0140-6736(02)09290-5.CrossRefGoogle Scholar
- 21.D’Annibale A, Morpurgo E, Fiscon V, Trevisan P, Sovernigo G, Orsini C, et al. Robotic and laparoscopic surgery for treatment of colorectal diseases. Dis Colon rectum. December 2004;47(12):2162–8. https://doi.org/10.1007/s10350-004-0711-z.
- 23.Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC Trial): multicentre, randomised controlled trial. Lancet (London, England). May 14, 2005;365(9472):1718–26. https://doi.org/10.1016/S0140-6736(05)66545-2.CrossRefGoogle Scholar
- 24.Thorpe, H., D. G. Jayne, P. J. Guillou, P. Quirke, J. Copeland, J. M. Brown, and Medical Research Council Conventional versus Laparoscopic-Assisted Surgery In Colorectal Cancer Trial Group. “Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer.” The British Journal of Surgery 95, no. 2 (February 2008): 199–205. doi: https://doi.org/10.1002/bjs.5907.