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Perianal Basal Cell Carcinoma: a Case Report

  • Marshall W. Meeks
  • Shane Grace
  • Grace Montenegro
  • Martin W. Schoen
  • Danielle Carpenter
  • Jin-Ping Lai
  • Nishant Poddar
Case Report
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Introduction

Basal cell carcinoma (BCC) is the most commonly diagnosed skin cancer and highest incidence of any malignancy in the USA [1]. It usually arises in the elderly on sun-exposed areas, such as the head and neck [2]. The most important etiologic factor for the development of BCC is ultraviolet light exposure; thus, it is very rare for BCC to arise within the anogenital region or other non-UV-exposed areas.

Here, we describe a case of a 49-year-old patient with a perianal skin lesion that presented with painless bleeding. Immunohistochemical staining for Ber-EP4 and BCL2 was positive which demonstrated that the lesion was BCC and not a basaloid squamous cell carcinoma. There have only been a few previously published reports of perianal BCC. While very rare, it is important to highlight this case as it demonstrates the necessity to biopsy suspicious perianal lesions and how to distinguish between basaloid squamous cell carcinoma and BCC.

Case Report

A 49-year-old Caucasian male...

Notes

Acknowledgements

The authors would like to thank Catherine Ellert for the help with manuscript preparation.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that there is no conflict of interest.

Informed Consent

Informed consent to publish this study was obtained from the patient.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Marshall W. Meeks
    • 1
  • Shane Grace
    • 1
  • Grace Montenegro
    • 2
  • Martin W. Schoen
    • 1
  • Danielle Carpenter
    • 3
  • Jin-Ping Lai
    • 4
  • Nishant Poddar
    • 1
  1. 1.Department of Internal MedicineSaint Louis University School of MedicineSt LouisUSA
  2. 2.Department of General SurgerySaint Louis University School of MedicineSaint LouisUSA
  3. 3.Department of PathologySaint Louis University School of MedicineSaint LouisUSA
  4. 4.Department of PathologyUniversity of FloridaGainesvilleUSA

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