Perianal Basal Cell Carcinoma: a Case Report
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Basal cell carcinoma (BCC) is the most commonly diagnosed skin cancer and highest incidence of any malignancy in the USA . It usually arises in the elderly on sun-exposed areas, such as the head and neck . The most important etiologic factor for the development of BCC is ultraviolet light exposure; thus, it is very rare for BCC to arise within the anogenital region or other non-UV-exposed areas.
Here, we describe a case of a 49-year-old patient with a perianal skin lesion that presented with painless bleeding. Immunohistochemical staining for Ber-EP4 and BCL2 was positive which demonstrated that the lesion was BCC and not a basaloid squamous cell carcinoma. There have only been a few previously published reports of perianal BCC. While very rare, it is important to highlight this case as it demonstrates the necessity to biopsy suspicious perianal lesions and how to distinguish between basaloid squamous cell carcinoma and BCC.
A 49-year-old Caucasian male...
The authors would like to thank Catherine Ellert for the help with manuscript preparation.
Compliance with Ethical Standards
Conflict of Interest
The authors declare that there is no conflict of interest.
Informed consent to publish this study was obtained from the patient.
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