Liver Metastatic Melanoma: a Unique Case with Normal Alkaline Phosphatase and Melanuria

  • Bao X. Nguyen
  • Vincent S. Petros
  • Judith F. Aronson
  • Lindsay K. Sonstein
Case Report
  • 12 Downloads

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from patient’s medical power of attorney.

References

  1. 1.
    Tuker MA. Melanoma epidemiology. Hematol Oncol Clin North Am. 2009;23:383–95.  https://doi.org/10.1016/j.hoc.2009.03.010.CrossRefGoogle Scholar
  2. 2.
    Rose DM, Essner R, Hughes TM, Tang PC, Bilchik A, Wanek LA, et al. Surgical resection for metastatic melanoma to the liver: the John Wayne Cancer Institute and Sydney Melanoma Unit experience. Arch Surg. 2001;136:950–05.CrossRefPubMedGoogle Scholar
  3. 3.
    Bouloux PM, Scott RJ, Goligher JE, Kindell C. Fulminant hepatic failure secondary to diffuse liver infiltration by melanoma. J R Soc Med. 1986;79:302–3.  https://doi.org/10.1177/014107688607900513.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, et al. Acute hepatic failure secondary to extensive hepatic replacement by metastatic amelanotic melanoma: an autopsy case report. Clin J Gastroenterol. 2010;3:327–31.  https://doi.org/10.1007/s12328-010-0181-x.CrossRefPubMedGoogle Scholar
  5. 5.
    Kaplan GG, Medlicott S, Culleton B, Laupland KB. Acute hepatic failure and multi-system organ failure secondary to replacement of the liver with metastatic melanoma. BMC Cancer. 2005;5:67.  https://doi.org/10.1186/1471-2407-5-67.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Mashayekhi S, Gharaie S, Hajhosseiny R, Patel K. A rare presentation of malignant melanoma with acute hepatic and consecutive multisystem organ failure. Int J Dermatol. 2014;53:e330–1.  https://doi.org/10.1111/ijd.12268.CrossRefPubMedGoogle Scholar
  7. 7.
    Montero JL, Muntane J, de las Heras D, Ortega R, Fraga E, De la Mata M. Acute liver failure caused by diffuse hepatic melanoma infiltration. J Hepatol. 2002;37:540–1.CrossRefPubMedGoogle Scholar
  8. 8.
    Rubio S, Barbero-Villares A, Reina T, Nieto S, Mendoza J, Garcia-Buey L. Rapidly-progressive liver failure secondary to melanoma infiltration. Gastroenterol Hepatol. 2005;28:619–21.CrossRefPubMedGoogle Scholar
  9. 9.
    Schlevogt B, Rhekamper J, Hild B, Schmidt H. Hepatobiliary and pancreatic: fulminant liver failure from diffuse leukemoid hepatic infiltration of melanoma. J Gastroenterol Hepatol. 2017;32:1795.  https://doi.org/10.1111/jgh.13904.CrossRefPubMedGoogle Scholar
  10. 10.
    Shan GD, Xu GQ, Chen LH, Wang ZM, Jin EY, Hu FL, et al. Diffuse liver infiltration by melanoma of unknown primary origin: one case report and literature review. Intern Med. 2009;48:2093–6.CrossRefPubMedGoogle Scholar
  11. 11.
    Tanaka K, Tomita H, Hisamatsu K, Hatano Y, Yoshida K, Hara A. Acute liver failure associated with diffuse hepatic infiltration of malignant melanoma of unknown primary origin. Intern Med. 2015;54:1361–4.  https://doi.org/10.2169/internalmedicine.54.3428.CrossRefPubMedGoogle Scholar
  12. 12.
    Tanaka M, Watanabe S, Masaki T, Kurokohchi K, Kinekawa F, Inoue H, et al. Fulminant hepatic failure caused by malignant melanoma of unknown primary origin. J Gastroenterol. 2004;39:804–6.  https://doi.org/10.1007/s00535-003-1379-1.PubMedGoogle Scholar
  13. 13.
    Te HS, Chiano TD, Kahaleh M, Lissoos TW, Baker A, Hart J, et al. Fulminant hepatic failure secondary to malignant melanoma: case report and review of the literature. Am J Gastroenterol. 1999;94:262–6.  https://doi.org/10.1111/j.1572-0241.1999.00811.x.CrossRefPubMedGoogle Scholar
  14. 14.
    Kurtz AB, Rubin CS, Copper HS, Nisenbaum HL, Cole-Beuglet C, Medoff J, et al. Ultrasound findings in hepatitis. Radiology. 1980;136:717–23.  https://doi.org/10.1148/radiology.136.3.7403553.CrossRefPubMedGoogle Scholar
  15. 15.
    Needleman L, Kurtz AB, Rifkin MD, Cooper HS, Pasto ME, Goldberg BB. Sonography of diffuse benign liver disease: accuracy of pattern recognition and grading. AJR Am J Roentgenol. 1986;146:1011–5. https://www.ajronline.org/doi/10.2214/ajr.146.5.1011 CrossRefPubMedGoogle Scholar
  16. 16.
    Sabatine MS. Pocket medicine: the Massachusetts General Hospital handbook of internal medicine, vol. 3. 6th ed. Philadelphia: Wolters Kluwer; 2017. p. 16.Google Scholar
  17. 17.
    Gambichler T, Stucker M, Kerner K, Weiner S, Waldherr R, Altmeyer P, et al. Acute kidney injury in a patient with melanuria, diffuse melanosis and metastatic malignant melanoma. Am J Clin Dermatol. 2008;9:267–70.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Bao X. Nguyen
    • 1
  • Vincent S. Petros
    • 1
  • Judith F. Aronson
    • 2
  • Lindsay K. Sonstein
    • 1
  1. 1.Department of Internal MedicineUniversity of Texas Medical BranchGalvestonUSA
  2. 2.Department of PathologyUniversity of Texas Medical BranchGalvestonUSA

Personalised recommendations