Skip to main content

Advertisement

SpringerLink
Log in

Liver Metastatic Melanoma: a Unique Case with Normal Alkaline Phosphatase and Melanuria

  • Case Report
  • Published:
Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Tuker MA. Melanoma epidemiology. Hematol Oncol Clin North Am. 2009;23:383–95. https://doi.org/10.1016/j.hoc.2009.03.010.

    Article  Google Scholar 

  2. Rose DM, Essner R, Hughes TM, Tang PC, Bilchik A, Wanek LA, et al. Surgical resection for metastatic melanoma to the liver: the John Wayne Cancer Institute and Sydney Melanoma Unit experience. Arch Surg. 2001;136:950–05.

    Article  CAS  PubMed  Google Scholar 

  3. Bouloux PM, Scott RJ, Goligher JE, Kindell C. Fulminant hepatic failure secondary to diffuse liver infiltration by melanoma. J R Soc Med. 1986;79:302–3. https://doi.org/10.1177/014107688607900513.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  4. Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, et al. Acute hepatic failure secondary to extensive hepatic replacement by metastatic amelanotic melanoma: an autopsy case report. Clin J Gastroenterol. 2010;3:327–31. https://doi.org/10.1007/s12328-010-0181-x.

    Article  PubMed  Google Scholar 

  5. Kaplan GG, Medlicott S, Culleton B, Laupland KB. Acute hepatic failure and multi-system organ failure secondary to replacement of the liver with metastatic melanoma. BMC Cancer. 2005;5:67. https://doi.org/10.1186/1471-2407-5-67.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Mashayekhi S, Gharaie S, Hajhosseiny R, Patel K. A rare presentation of malignant melanoma with acute hepatic and consecutive multisystem organ failure. Int J Dermatol. 2014;53:e330–1. https://doi.org/10.1111/ijd.12268.

    Article  PubMed  Google Scholar 

  7. Montero JL, Muntane J, de las Heras D, Ortega R, Fraga E, De la Mata M. Acute liver failure caused by diffuse hepatic melanoma infiltration. J Hepatol. 2002;37:540–1.

    Article  PubMed  Google Scholar 

  8. Rubio S, Barbero-Villares A, Reina T, Nieto S, Mendoza J, Garcia-Buey L. Rapidly-progressive liver failure secondary to melanoma infiltration. Gastroenterol Hepatol. 2005;28:619–21.

    Article  CAS  PubMed  Google Scholar 

  9. Schlevogt B, Rhekamper J, Hild B, Schmidt H. Hepatobiliary and pancreatic: fulminant liver failure from diffuse leukemoid hepatic infiltration of melanoma. J Gastroenterol Hepatol. 2017;32:1795. https://doi.org/10.1111/jgh.13904.

    Article  CAS  PubMed  Google Scholar 

  10. Shan GD, Xu GQ, Chen LH, Wang ZM, Jin EY, Hu FL, et al. Diffuse liver infiltration by melanoma of unknown primary origin: one case report and literature review. Intern Med. 2009;48:2093–6.

    Article  PubMed  Google Scholar 

  11. Tanaka K, Tomita H, Hisamatsu K, Hatano Y, Yoshida K, Hara A. Acute liver failure associated with diffuse hepatic infiltration of malignant melanoma of unknown primary origin. Intern Med. 2015;54:1361–4. https://doi.org/10.2169/internalmedicine.54.3428.

    Article  PubMed  Google Scholar 

  12. Tanaka M, Watanabe S, Masaki T, Kurokohchi K, Kinekawa F, Inoue H, et al. Fulminant hepatic failure caused by malignant melanoma of unknown primary origin. J Gastroenterol. 2004;39:804–6. https://doi.org/10.1007/s00535-003-1379-1.

    Article  PubMed  Google Scholar 

  13. Te HS, Chiano TD, Kahaleh M, Lissoos TW, Baker A, Hart J, et al. Fulminant hepatic failure secondary to malignant melanoma: case report and review of the literature. Am J Gastroenterol. 1999;94:262–6. https://doi.org/10.1111/j.1572-0241.1999.00811.x.

    Article  CAS  PubMed  Google Scholar 

  14. Kurtz AB, Rubin CS, Copper HS, Nisenbaum HL, Cole-Beuglet C, Medoff J, et al. Ultrasound findings in hepatitis. Radiology. 1980;136:717–23. https://doi.org/10.1148/radiology.136.3.7403553.

    Article  CAS  PubMed  Google Scholar 

  15. Needleman L, Kurtz AB, Rifkin MD, Cooper HS, Pasto ME, Goldberg BB. Sonography of diffuse benign liver disease: accuracy of pattern recognition and grading. AJR Am J Roentgenol. 1986;146:1011–5. https://www.ajronline.org/doi/10.2214/ajr.146.5.1011

    Article  CAS  PubMed  Google Scholar 

  16. Sabatine MS. Pocket medicine: the Massachusetts General Hospital handbook of internal medicine, vol. 3. 6th ed. Philadelphia: Wolters Kluwer; 2017. p. 16.

    Google Scholar 

  17. Gambichler T, Stucker M, Kerner K, Weiner S, Waldherr R, Altmeyer P, et al. Acute kidney injury in a patient with melanuria, diffuse melanosis and metastatic malignant melanoma. Am J Clin Dermatol. 2008;9:267–70.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA

    Bao X. Nguyen, Vincent S. Petros & Lindsay K. Sonstein

  2. Department of Pathology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA

    Judith F. Aronson

Authors
  1. Bao X. Nguyen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vincent S. Petros
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Judith F. Aronson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Lindsay K. Sonstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Lindsay K. Sonstein.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from patient’s medical power of attorney.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nguyen, B.X., Petros, V.S., Aronson, J.F. et al. Liver Metastatic Melanoma: a Unique Case with Normal Alkaline Phosphatase and Melanuria. J Gastrointest Canc 50, 621–624 (2019). https://doi.org/10.1007/s12029-018-0090-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12029-018-0090-7

Keywords

Search

Navigation