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Immunologic Research

, Volume 65, Issue 1, pp 282–284 | Cite as

Postural tachycardia syndrome (POTS) with anti-NMDA receptor antibodies after human papillomavirus vaccination

  • Svetlana Blitshteyn
  • Jill Brook
Therapeutic Aspects in Autoimmunity

Abstract

We describe a young woman who developed POTS with positive serum anti-NMDA receptor antibodies and no evidence of encephalitis after vaccination with HPV vaccine, Cervarix. Her symptoms improved significantly with immunomodulatory therapy and re-occurred after immunomodulatory therapy was stopped, suggesting an autoimmune etiology of POTS after vaccination.

Keywords

Human papillomavirus vaccination Postural tachycardia syndrome Anti-NMDA receptor antibodies Orthostatic intolerance Plasmapheresis 

Notes

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of NeurologyState University of New York at Buffalo School of Medicine and Biomedical SciencesBuffaloUSA
  2. 2.Department of PsychologyUniversity of California, Los AngelesLos AngelesUSA

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