Endocrine Pathology

, Volume 29, Issue 1, pp 86–88 | Cite as

Antidepressant-Related Black Thyroid

  • Jean-Luc Barras
  • Rossella Sarro
  • Massimo Bongiovanni
  • Stefano La Rosa

Case History

In 2010, a 61-year-old Caucasian woman presented with a palpable thyroid goiter associated with hyperthyroidism and started carbimazole therapy. Her medical history also included long standing anxious-depressive troubles treated with lithium and tricyclic antidepressants for several years and, successively, with paroxetine. In addition, she suffered of type 2 diabetes mellitus, arterial hypertension, mixed dyslipidemia, and osteoporosis. She never used minocycline or related tetracycline antibiotics. She underwent thyroid scintigraphy that showed a hot left nodule and a cold right nodule. Fine needle aspiration (FNA) of both nodules was performed. Unfortunately, FNA of the right nodule was non-diagnostic, while the left one was benign. Then, she disappeared from clinical surveillance and 6 years later, she presented to her general practitioner who, on the basis of her psychiatric troubles which made her unable to follow the correct thyroid therapy, suggested a complete...


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Jean-Luc Barras
    • 1
  • Rossella Sarro
    • 1
  • Massimo Bongiovanni
    • 1
  • Stefano La Rosa
    • 1
  1. 1.Service of Clinical PathologyLausanne University Hospital, Institute of PathologyLausanneSwitzerland

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