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Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population

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Abstract

Purpose

This study aimed to investigate independent relationships of daily non-exercise life activity and leisure-time exercise volume and intensity with the prevalence of metabolic syndrome and its traits in Japanese adults.

Methods

Data of 24,625 eligible subjects (12,709 men, 11,916 women) who participated in the baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study were analyzed. Information about lifestyle characteristics was obtained from a questionnaire. Logistic regression analyses were performed to evaluate the independent associations of daily life activity as well as leisure-time exercise volume and intensity with the prevalence of metabolic syndrome and its traits by sex.

Results

Male subjects with higher daily life activity as well as with higher leisure-time exercise volume had a lower prevalence of metabolic syndrome, independently with each other. Female subjects with higher daily life activity also had a lower prevalence of metabolic syndrome. Particularly, male and female subjects with the highest daily life activity quartile showed considerably low odds ratios of 0.66 (95% CI, 0.53–0.81) and 0.64 (0.52–0.79), respectively, for low HDL-cholesterol even after the adjustment for BMI compared with the first quartile. Meanwhile, male subjects with the higher leisure-time exercise showed a quite lower prevalence of elevated triglycerides. Higher moderate-intensity exercise was more intensely associated with a lower prevalence of metabolic syndrome and some of its traits in both sexes.

Conclusions

Our results suggest that higher daily life activity and higher moderate-intensity exercise may be independently associated with a lower risk of metabolic syndrome in Japanese adults.

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Acknowledgements

This study was funded by Grants-in-Aid for Scientific Research on Priority Areas of Cancer (No. 17015018), on Innovative Areas (No. 221S0001), and Platform of Supporting Cohort Study and Biospecimen Analysis (JSPS KAKENHI Grant Number JP16H06277) from the Japanese Ministry of Education, Culture, Sports, Science and Technology, and by Grants-in-Aid for Scientific Research (C) (JSPS KAKENHI Grant Numbers JP15K08778 and JP18K10086) from the Japan Society for the Promotion of Science.

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Authors and Affiliations

  1. Department of Preventive Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

    Hirokazu Uemura, Sakurako Katsuura-Kamano, Yuki Iwasaki & Kokichi Arisawa

  2. Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Asahi Hishida, Rieko Okada, Takashi Tamura, Yoko Kubo, Mariko Naito & Kenji Wakai

  3. Division of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, Japan

    Hidemi Ito

  4. Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan

    Isao Oze

  5. Clinical Research Center, Saga University Hospital, Saga, Japan

    Chisato Shimanoe

  6. Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan

    Yuichiro Nishida

  7. Department of Food Science and Human Nutrition, Faculty of Agriculture, Ryukoku University, Otsu, Japan

    Yasuyuki Nakamura

  8. Department of Public Health, Shiga University of Medical Science, Otsu, Japan

    Naoyuki Takashima

  9. Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

    Sadao Suzuki & Hiroko Nakagawa-Senda

  10. Kagoshima University School of Health Sciences, Kagoshima, Japan

    Daisaku Nishimoto

  11. Department of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Toshiro Takezaki

  12. Cancer Prevention Center, Chiba Cancer Center Research Institute, Chiba, Japan

    Haruo Mikami & Yohko Nakamura

  13. Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan

    Norihiro Furusyo & Hiroaki Ikezaki

  14. Department of Environmental Medicine and Infectious Disease, Kyushu University, Fukuoka, Japan

    Norihiro Furusyo & Hiroaki Ikezaki

  15. Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Etsuko Ozaki & Teruhide Koyama

  16. Laboratory of Public Health, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan

    Kiyonori Kuriki & Kaori Endoh

  17. Department of Oral Epidemiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    Mariko Naito

Authors
  1. Hirokazu Uemura
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for the Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group

Corresponding author

Correspondence to Hirokazu Uemura.

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The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the ethics committees of Nagoya University Graduate School of Medicine, Japan, Tokushima University Graduate School, Japan and other participating institutions, conducted in accordance with the principles of the Declaration of Helsinki, and performed in accordance with the relevant guidelines and regulations.

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Informed consent was obtained from all individual participants included in the study.

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Uemura, H., Katsuura-Kamano, S., Iwasaki, Y. et al. Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population. Endocrine 64, 552–563 (2019). https://doi.org/10.1007/s12020-019-01926-9

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  • DOI: https://doi.org/10.1007/s12020-019-01926-9

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