Gain-of-function SNPs in NLRP3 and IL1B genes confer protection against obesity and T2D: undiscovered role of inflammasome genetics in metabolic homeostasis?
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This study was supported by Sao Paulo Research Foundation (FAPESP) (Grants numbers: 2015/23395-6;) and “Conselho Nacional de Desenvolvimento Cientıfico e Tecnologico” (CNPq). A.P. is a recipient of a CNPq fellowship. J.M.R. was a recipient of a PIBIC Fellowship. V.N.C.L. is a recipient of a FAPESP-funded fellowship. D.L. is a recipient of a UFAM-funded PhD Fellowship.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no competing interests.
Research involved human participants. All procedures performed were in accordance with the ethical standards of the Institutional Review Board of the “Santa Casa de Belo Horizonte” hospital, and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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