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Refractory Arrhythmias in a Young Patient Poisoned by Imipramine

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Abstract

Tricyclic antidepressants are used to treat a variety of mental disorders, and are considered a common cause of fatal drug poisoning. This study reports a young woman with no history of cardiac diseases who presented to the emergency department with heart palpitation, weakness, and lethargy. After a short period of time, she became unconscious and experienced hypotension and refractory arrhythmia, finally being diagnosed with imipramine poisoning. Accurate history taking and the possible causes of these complications including cardio-toxic drug poisoning should be considered in such patients.

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Authors and Affiliations

  1. Cardiovascular Diseases Research Center, Department of Cardiology, School of Medicine, Birjand University of Medical Science, Birjand, Iran

    Nahid Azdaki

  2. Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran

    Samaneh Nakhaee & Omid Mehrpour

  3. Department of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Nasim Zamani

  4. Rocky Mountain Poison and Drug Center, Denver, CO, USA

    Omid Mehrpour

Authors
  1. Nahid Azdaki
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  2. Samaneh Nakhaee
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  3. Nasim Zamani
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  4. Omid Mehrpour
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Corresponding author

Correspondence to Omid Mehrpour.

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Handling Editor: Y. James Kang.

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Azdaki, N., Nakhaee, S., Zamani, N. et al. Refractory Arrhythmias in a Young Patient Poisoned by Imipramine. Cardiovasc Toxicol 19, 90–93 (2019). https://doi.org/10.1007/s12012-018-9477-8

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  • DOI: https://doi.org/10.1007/s12012-018-9477-8

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