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Long-term chromium picolinate supplementation improves colostrum profile of Santa Ines ewe

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Abstract

Chromium (Cr) is a micromineral that is involved in the metabolism of carbohydrates, lipids, ammonia, and nucleic acids; thus, its supplementation can influence the nutritional status of ruminants, and consequently, colostrum profile, since this secretion depends on products secreted by the mammary gland and elements of the maternal bloodstream. The present study investigated the influence of supplementation with Cr bound to organic molecule on the nutritional, immune, and antioxidant quality of ewe colostrum. Thirty-two multiparous Santa Ines ewes (55.3 ± 8.00 kg body weight) were randomly assigned into four groups: T1 (0.0 mg of chromium picolinate (CrPic) supplementation per ewe, n = 8), T2 (0.15 mg of CrPic per ewe, n = 9), T3 (0.30 mg of CrPic per ewe, n = 7), and T4 (0.45 mg of CrPic per ewe, n = 8). Supplementation was supplied during the breeding season, pregnancy, and lactation. Shortly after calving, the first milking colostrum was collected to determine its chemical composition, activity of lysozyme, lactoperoxidase, ceruloplasmin, catalase, glutathione peroxidase, and oxygen radical absorbance capacity. The results show that lactoperoxidase activity decreased with CrPic supplementation (P < 0.01), revealing that this micromineral reduces an important component of defense mechanism in the body. Therefore, the results of this work show that supplementation with chromium picolinate influences colostrum quality.

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Funding

Authors are indebted to Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).

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Authors and Affiliations

  1. Animal Science Laboratory, Center for Nuclear Energy in Agriculture, University of Sao Paulo, 303, Centenario Avenue, 13416-000, Piracicaba, Sao Paulo, Brazil

    Thiago F. V. Bompadre, Gabriel Z. Sakita, Egon H. Ieda, Adibe L. Abdalla & Helder Louvandini

  2. Animal Science Department, Luiz de Queiroz College of Agriculture, University of Sao Paulo, 11, Padua Dias Avenue, Piracicaba, Sao Paulo, Brazil

    Débora B. Moretti & Raul Machado-Neto

  3. Radioisotopes Laboratory, Centre for Nuclear Energy in Agriculture, University of Sao Paulo, 303, Centenario Avenue, Piracicaba, Sao Paulo, Brazil

    Maria I. V. Martinez & Elisabete A. N. Fernandes

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  1. Thiago F. V. Bompadre
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  9. Helder Louvandini
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Correspondence to Helder Louvandini.

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The project was approved by the Ethics Committee on Animal Use (CENA/USP—007-2016) and conducted in accordance with the rules of Waste Management of ESALQ/USP.

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Bompadre, T.F.V., Moretti, D.B., Sakita, G.Z. et al. Long-term chromium picolinate supplementation improves colostrum profile of Santa Ines ewe. Biol Trace Elem Res 193, 414–421 (2020). https://doi.org/10.1007/s12011-019-01741-3

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