Biological Trace Element Research

, Volume 176, Issue 2, pp 244–250 | Cite as

Evaluation of the Relationship Between Height and Zinc, Copper, Iron, Calcium, and Magnesium Levels in Healthy Young Children in Beijing, China

  • Yan Yin
  • Yongjin Li
  • Qin Li
  • Ni Jia
  • Aihua Liu
  • Zangwen Tan
  • Qiong Wu
  • Zhaoyang Fan
  • Tao Li
  • Lijun Wang


We evaluated the relationship between child (aged 6–36 months) height and blood zinc, copper, iron, calcium, and magnesium concentrations. We selected 840 children following a physical examination. Weight and supine length or standing height were measured according to the World Health Organization guidelines. Polarographic analysis was used to measure zinc, copper, iron, magnesium, and calcium levels. Differences in heights between groups with low vs. high mineral concentrations, stratified by sex and age, were compared by analysis of variance. Relationships between these five elements and heights were tested by multiple regression analysis. Zinc levels in the shorter group (height for age (HAZ) ≤ −0.3) were 135.84 ± 39.76 and 134.83 ± 37.57 μmol/L in boys and girls, respectively. Zinc concentrations in the taller group (HAZ > −0.3) were 142.50 ± 35.85 and 140.52 ± 35.80 μmol/L in boys and girls, respectively. The difference between the two height groups in boys and girls was statistically significant. Compared with those (143.06 ± 33.76 μmol/L) in the taller group, zinc concentration (131.30 ± 40.75 μmol/L) in the shorter group was significantly lower (p = 0.04) at age 6–12 months. Height was positively correlated with zinc level in children aged 6–12 months (p < 0.05). Zinc levels were positively correlated with calcium, magnesium, and iron concentrations in children aged 6–36 months (p < 0.05). Our results indicated that zinc levels and height are correlated, and zinc levels were related to calcium, magnesium, copper, and iron concentrations. Therefore, to ensure healthy development in children, blood levels of these five elements should be balanced.


Child Height Mineral levels Calcium 



The study was supported by the National Natural Science Foundation of China (grant number 81202219) of the People’s Republic of China.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Yan Yin
    • 1
  • Yongjin Li
    • 2
  • Qin Li
    • 3
  • Ni Jia
    • 1
  • Aihua Liu
    • 1
  • Zangwen Tan
    • 1
  • Qiong Wu
    • 1
  • Zhaoyang Fan
    • 1
  • Tao Li
    • 1
  • Lijun Wang
    • 1
  1. 1.Integrated Early Childhood DevelopmentCapital Institute of PediatricsBeijingChina
  2. 2.Tuanjiehu Community Health Service CenterBeijingChina
  3. 3.Environmental Standards InstituteChinese Research Academy of Environmental SciencesBeijingChina

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