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Synthesis, Characterization, and Antimicrobial Activity of Poly(acrylonitrile-co-methyl methacrylate) with Silver Nanoparticles

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Abstract

Nanotechnology is expected to open some new aspects to fight and prevent diseases using atomic-scale tailoring of materials. The main aim of this study is to biosynthesize silver nanoparticles (AgNPs) using Trichoderma viride (HQ438699); the metabolite of this fungus will help either in reduction of the silver nitrate-adding active materials which will be loaded on the surface of the produced AgNPs. Poly(acrylonitrile-co-methyl methacrylate) copolymer (poly (AN-co-MMA)) was grafted with the prepared AgNPs. The poly(AN-co-MMA)/AgNPs were examined against ten different pathogenic bacterial strains, and the result was compared with another four different generic antibiotics. The produced poly(AN-co-MMA)/AgNPs showed high antibacterial activity compared with the four standard antibiotics. Moreover, the grafting of these AgNPs into the copolymer has potential application in the biomedical field.

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Acknowledgments

The authors extend their appreciation to the Deanship of Scientific Research at King Saud University for funding this work through research group no. RGP-VPP-201.

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Authors and Affiliations

  1. Polymer Materials Research Department, Institute of Advanced Technology and New Material, City of Scientific Research and Technology Applications, New Borg El-Arab City, 21934, Alexandria, Egypt

    M. R. El-Aassar

  2. Plant Molecular Pathology, Arid Lands and Research Institute, City of Scientific Research and Technology Applications, New Borg El-Arab City, 21934, Alexandria, Egypt

    Elsayed E. Hafez

  3. Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia

    Moustafa M. G. Fouda & Salem S. Al-Deyab

  4. Textile Research Division, National Research Center, Dokki, Cairo, P.O. Box 12622, Giza, 12522, Egypt

    Moustafa M. G. Fouda

Authors
  1. M. R. El-Aassar
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  2. Elsayed E. Hafez
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  3. Moustafa M. G. Fouda
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  4. Salem S. Al-Deyab
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Correspondence to M. R. El-Aassar.

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El-Aassar, M.R., Hafez, E.E., Fouda, M.M.G. et al. Synthesis, Characterization, and Antimicrobial Activity of Poly(acrylonitrile-co-methyl methacrylate) with Silver Nanoparticles. Appl Biochem Biotechnol 171, 643–654 (2013). https://doi.org/10.1007/s12010-013-0395-8

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  • DOI: https://doi.org/10.1007/s12010-013-0395-8

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