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Case Report: Bone Tumor of the Scapula in a Patient Undergoing Liver Transplantation

  • Case Report
  • Published:
Clinical Orthopaedics and Related Research®

Abstract

Background

De novo malignancies are serious complications in the late postoperative period after liver transplantation. The most common de novo tumors are skin malignancies, posttransplantation lymphoproliferative disorder, tumors of the head and neck, and Kaposi’s sarcoma. Such posttransplant de novo malignancies are apparently rarely found in bone.

Case Description

We describe a patient with a low-grade, aggressive fibrous histiocytoma of the scapula. The patient had undergone liver transplantation 6 years earlier. En bloc resection of the tumor and limb salvage was performed. At the 2-year followup the patient had no signs of local recurrence or metastatic spread; the patient had a Musculoskeletal Tumor Society (MSTS) score of 87.

Literature Review

A literature review suggests the main predisposing factors to such malignancies are immunosuppression and its length of use. According to the literature, tumors apparently are rare in bone after liver transplantation, with no clearly documented cases. However, in the presence of such a finding, our study might be the first clearly documented case study of this kind of bone tumor.

Clinical Relevance

We describe a patient with a bone tumor after liver transplantation. Our literature review suggests liver transplantation and long-term immunosuppression played a role in this patient’s tumor.

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Acknowledgment

We thank the patient’s guardian for granting informed written consent for publication and electronic publication of this case report.

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Authors and Affiliations

  1. Department of Orthopedics, 175th Hospital of the PLA, Xiamen University Affiliated Hospital, Zhangzhou, 363000, Fujian, China

    Zhen-Qi Ding MD, Liang-Qi Kang MD & Mo Sha MD

  2. Department of Pathology, Xiamen University Affiliated 1st Hospital, Xia’men, Fujian, China

    Hai-Fang Zhang MD

Authors
  1. Zhen-Qi Ding MD
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  2. Hai-Fang Zhang MD
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  3. Liang-Qi Kang MD
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  4. Mo Sha MD
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Corresponding author

Correspondence to Mo Sha MD.

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Each author certifies that he or she, or a member of their immediate family, has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research editors and board members are on file with the publication and can be viewed on request.

Each author certifies that his or her institution approved the reporting of this case report, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained.

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Ding, ZQ., Zhang, HF., Kang, LQ. et al. Case Report: Bone Tumor of the Scapula in a Patient Undergoing Liver Transplantation. Clin Orthop Relat Res 470, 1232–1235 (2012). https://doi.org/10.1007/s11999-011-2236-9

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  • DOI: https://doi.org/10.1007/s11999-011-2236-9

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