Food and Bioprocess Technology

, Volume 12, Issue 7, pp 1110–1122 | Cite as

Chlorine Dioxide Generation Method and Its Action Mechanism for Removing Harmful Substances and Maintaining Quality Attributes of Agricultural Products

  • Yan Ran
  • Chen Qingmin
  • Fu MaorunEmail author
Original Paper


Agricultural products are perishable and easily contaminated by spoilage microorganisms or foodborne pathogens, causing decay of food and illness in consumers. Chlorine dioxide (ClO2) has many advantages as a fungicide in comparison to chlorine, NaClO, and ozone, and it can be used for sterilization and preservation due to its strong oxidizing properties. ClO2 gas is more widely used in food safety and food preservation than its aqueous solutions. However, the ClO2 gas produced on a large scale from a chemical reactor cannot be applied to food in small packages. Several recent reports have discussed the use of ClO2 self-releasing packaging. This article highlights the systematic evaluation of the performance of ClO2 alone and in combination with other treatments, such as 1-MCP, chitosan, and UV irradiation, in maintaining food safety and freshness of agricultural products. This article also focuses on the biological functions and mechanisms of ClO2-mediated preservation of plant or animal food, including damage to the cell wall and the membrane of pathogens, inhibition of ethylene biosynthesis, restoration of redox balance, and change of the compound structure of toxins, such as pesticides, insecticides, and mycotoxins.


Chlorine dioxide Food preservation Application methods Action mechanisms Safety assurance 


Funding Information

This research project was financially supported by the National Science Foundation of China (Project No. 31871854).


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.School of Food Science and EngineeringQilu University of Technology (Shandong Academy of Sciences)JinanPeople’s Republic of China
  2. 2.Department of Food Science and EngineeringShandong Agriculture and Engineering UniversityJinanPeople’s Republic of China

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