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Pediatric Antimicrobial Stewardship: State of the Art

  • Healthcare Associated Infections (G Bearman and D Morgan, Section Editors)
  • Published:
Current Infectious Disease Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We aim to systematically review the literature on the effectiveness of pediatric antimicrobial stewardship programs (ASPs) and antimicrobial stewardship (AS) strategies in the United States (US) inpatient setting. Furthermore, we review current gaps and challenges for unique pediatric populations and those in ambulatory settings.

Recent Findings

Misuse and overuse of antimicrobials have been identified as key factors for antimicrobial resistance (AR). Multiple professional organizations support the implementation of hospital-based ASPs to decrease antimicrobial consumption, improve patient outcomes, and reduce healthcare costs. There is limited data on the effectiveness of inpatient pediatric ASPs and AS strategies in unique populations. Furthermore, there is a paucity of evidence on ASPs in ambulatory settings.

Summary

This review contributes to the growing body of evidence that supports the use of pediatric ASPs to optimize antimicrobial therapy in the inpatient setting as well as in unique patient populations and ambulatory settings. Active stewardship is critical and antimicrobial consumption is a key outcome metric for programs.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Department of Pediatrics, Division of Pediatric Infectious Diseases, Children’s Hospital of Richmond at Virginia Commonwealth University Health System, Children’s Pavilion, 1000 East Broad St, PO Box 23298-0163, Richmond, VA, USA

    Emily J. Godbout

  2. Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA

    Amy L. Pakyz

  3. Department of Internal Medicine, Division of Infectious Disease, Veterans Affairs Medical Center, Virginia Commonwealth University Health System, Richmond, VA, USA

    John Daniel Markley & Michael P. Stevens

  4. Department of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USA

    Andrew J. Noda

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  1. Emily J. Godbout
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  2. Amy L. Pakyz
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Correspondence to Emily J. Godbout.

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This article is part of the Topical Collection on Healthcare Associated Infections

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Godbout, E.J., Pakyz, A.L., Markley, J.D. et al. Pediatric Antimicrobial Stewardship: State of the Art. Curr Infect Dis Rep 20, 39 (2018). https://doi.org/10.1007/s11908-018-0644-7

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