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Renal Denervation for Resistant Hypertension: Where Do We Stand?

  • Resistant Hypertension (L Drager, Section Editor)
  • Published:
Current Hypertension Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

To review the data about the use of renal denervation (RDN), a minimally invasive surgery, for resistant hypertension (RH) and to provide practical guidance for practitioners who are establishing an RDN service.

Recent Findings

RDN can selectively ablate renal sympathetic nerve fibres, block the transmission of nerve impulses between central sympathetic nerve and kidney, to control blood pressure to as a novel promising non-drug treatment option for RH. At present, there are many researches on the treatment of RH by RDN, but there are some controversies. This review summarises and critically examines the evidence for RDN in the treatment of RH and identifies areas for future research.

Summary

With the development of RDN, the continuous innovation of RDN technology and methods, the development about better evaluating the real-time success of RDN and the improvement for identifying individuals who are most likely to benefit from RDN will ultimately determine whether RDN represents a feasible way to manage RH in the future.

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Funding

This work was supported by the National Natural Science Foundation of China [81774229], Jiangsu Leading Talent Project of Traditional Chinese Medicine [Jiangsu TCM 2018 No. 4], Major Project of Nanjing Medical Science and Technology Development During 13th Five-year Plan [ZDX16013], and Jiangsu Universities Nursing Advantage Discipline Project [2019YSHL095].

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Correspondence to Ning Gu.

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This article is part of the Topical Collection on Resistant Hypertension

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Liang, B., Zhao, YX. & Gu, N. Renal Denervation for Resistant Hypertension: Where Do We Stand?. Curr Hypertens Rep 22, 83 (2020). https://doi.org/10.1007/s11906-020-01094-6

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