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Noninvasive Tests for Liver Fibrosis in Chronic Hepatitis B Virus

  • Topical Collection on Hepatitis B
  • Published:
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Abstract

Purpose of Review

Hepatitis B virus (HBV) can be a potentially life-threatening liver infection. Prior to starting therapy, the first step is to establish the diagnosis, then to assess disease severity and determine if treatment is indicated. Assessing the degree of liver fibrosis is imperative to guiding treatment options. While liver biopsy has been the primary method to establish the degree of fibrosis, noninvasive tests (NIT) have now replaced liver biopsy as the initial step.

Recent Findings

Here, we present a recent review of literature on NIT to assess liver fibrosis in chronic HBV from 2019 to 2022.

Summary

Being able to use NIT (blood- and/or imaging-based) to assess fibrosis and help guide treatment can help impact and lower disease burden as well as life-threatening complications of liver disease.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

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Authors and Affiliations

  1. Department of Internal Medicine, Virginia Commonwealth University Health System, Richmond, USA

    Nikita Chadha & Richard K. Sterling

  2. Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University System, West Hospital, 1200 E Broad StreetRm 1478, Richmond, VA, 23298-0341, USA

    Richard K. Sterling

Authors
  1. Nikita Chadha
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Correspondence to Richard K. Sterling.

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Chadha, N., Sterling, R.K. Noninvasive Tests for Liver Fibrosis in Chronic Hepatitis B Virus. Curr Hepatology Rep 21, 68–75 (2022). https://doi.org/10.1007/s11901-022-00592-2

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