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Hepatitis C Virus Treatment in Non-Liver Organ Transplantation Programs

  • Hepatitis C (A Aronsohn and H Vargas, Section Editors)
  • Published:
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Abstract

Purpose of Review

Solid organ transplantation is the treatment of choice for many patients with end organ damage. Hepatitis C (HCV) infection is prevalent among solid organ candidates and recipients and remains to be a significant source of morbidity and mortality for this population. New therapies are currently available for this population. In the following review, we will outline HCV treatment strategies in non-liver transplantation candidates and recipients.

Recent Findings

Direct-acting antivirals (DAAs) have drastically modified the treatment landscape of HCV. New DAA agents have been studied in patients with chronic diseases, transplantation candidates, and transplantation recipients.

Summary

The safety and efficacy of DAAs in patients awaiting liver transplantation and liver transplantation recipients has provided us with guidance on how to use them effectively for patients who received or are awaiting non-liver solid organ transplantations.

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Abbreviations

HCV:

Hepatitis C virus

DAAs:

Direct-acting antiviral agents

ESKD:

End-stage kidney disease

HD:

Hemodialysis

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Gastroenterology/Hepatology Fellowship, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Phoenix, AZ, USA

    Eduardo A. Rodriguez

  2. Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Phoenix, AZ, USA

    Bashar A. Aqel

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  1. Eduardo A. Rodriguez
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Correspondence to Bashar A. Aqel.

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Eduardo A. Rodriguez and Bashar A. Aqel declare no conflicts of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Hepatitis C

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Rodriguez, E.A., Aqel, B.A. Hepatitis C Virus Treatment in Non-Liver Organ Transplantation Programs. Curr Hepatology Rep 17, 105–110 (2018). https://doi.org/10.1007/s11901-018-0393-y

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  • DOI: https://doi.org/10.1007/s11901-018-0393-y

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