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Optimizing Cardiac Resynchronization Therapy: an Update on New Insights and Advancements

  • Pharmacologic Therapy (W.H.W. Tang, Section Editor)
  • Published:
Current Heart Failure Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

This review focuses on the current advancements in optimizing patient response to cardiac resynchronization therapy (CRT).

Recent Findings

It has been well known that not every patient will derive benefit from CRT, and of those that do, there are varying levels of response. Optimizing CRT begins well before device implant and involves appropriate patient selection and an understanding of the underlying substrate. After implant, there are different CRT device programming options that can be enabled to help overcome barriers as to why a patient may not respond.

Summary

Given the multifaceted components of optimizing CRT and the complex patient population, multi-subspecialty clinics have been developed bringing together specialists in heart failure, electrophysiology, and imaging. Data as to whether this results in better response rates and outcomes shows promise.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

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Author information

Authors and Affiliations

  1. Cardiology Fellowship, Cleveland Clinic Heart and Vascular Institute, Cleveland, OH, USA

    Adam Grimaldi

  2. Heart Failure, Cleveland Clinic Heart and Vascular Institute, Cleveland, OH, USA

    Eiran Z. Gorodeski

  3. Electrophysiology, Cleveland Clinic Heart and Vascular Institute, 9500 Euclid Avenue, J2-2, Cleveland, OH, USA

    John Rickard

Authors
  1. Adam Grimaldi
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  2. Eiran Z. Gorodeski
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  3. John Rickard
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Correspondence to John Rickard.

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Conflict of Interest

Adam Grimaldi and Eiran Z. Gorodeski declare no conflicts of interest. John Rickard reports personal fees from Medtronic and personal fees from Boston scientific, outside the submitted work.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Pharmacologic Therapy

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Grimaldi, A., Gorodeski, E.Z. & Rickard, J. Optimizing Cardiac Resynchronization Therapy: an Update on New Insights and Advancements. Curr Heart Fail Rep 15, 156–160 (2018). https://doi.org/10.1007/s11897-018-0391-y

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