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Current Diabetes Reports

, 17:110 | Cite as

Physical Exercise Improves Heart Rate Variability in Patients with Type 2 Diabetes: A Systematic Review

  • Santos Villafaina
  • Daniel Collado-Mateo
  • Juan Pedro Fuentes
  • Eugenio Merellano-Navarro
  • Narcis Gusi
Macrovascular Complications in Diabetes (VR Aroda and A Getaneh, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Macrovascular Complications in Diabetes

Abstract

Purpose of Review

The aim of the present systematic review is to provide an up-to-date analysis of the research on the effects of exercise programs on heart rate variability (HRV) in individuals with type 2 diabetes mellitus (T2DM). An electronic search of the literature (PubMed, PEDro and Web of Science) was performed. “HRV”, “heart rate variability”, “exercise”, “physical” and “diabetes” were the terms used for article retrieval. Lastly, 15 articles were selected. PRISMA methodology was employed and data were extracted according to the PICOS approach.

Recent Findings

Although HRV is not routinely measured in the management of T2DM, it is an important measure due to its relation with mortality and diabetic neuropathy. Physical exercise has become a therapy for T2DM, because it improves physical fitness and functional capacity, enhances metabolic control and insulin sensitivity, reduces inflammatory markers and neuropathy symptoms and can increase the regenerative capacity of cutaneous axons, slowing or preventing neuropathy progression. However, it is not clear to what extent physical exercise can improve HRV in this population.

Summary

Participation in the 15 selected studies was similar in men and women (48.01% men and 51.99% women). All the intervention programs included aerobic training, and it was complemented by strength training in four studies. Duration of physical exercise sessions ranged between 30 and 75 min, the frequency being between 2 and 7 days/week. Statistically significant improvements in groups with diabetes, relative to baseline, were observed in nine studies. More than 3 days per week of aerobic training, complemented by strength training, during at least 3 months seems to improve HRV in T2DM. Weekly frequency might be the most important factor to improve HRV. These aspects could help to design better programs based in scientific evidence, incorporating HRV as an important variable associated with diabetic neuropathy and mortality.

Keywords

Heart rate variability Type 2 diabetes Autonomic function Physical exercise 

Notes

Acknowledgements

The author DCM is supported by a grant from the Spanish Ministry of Education, Culture and Sport (FPU14/01283). Also, the author SV is supported by a grant from the regional Department of Economy and Infrastructure of the Government of Extremadura and European Social Fund (PD16008). The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.

Funding Sources

This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.

Compliance with Ethical Standards

Conflict of Interest

Santos Villafaina, Daniel Collado-Mateo, Juan Pedro Fuentes, Eugenio Merellano-Navarro and Narcis Gusi declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Supplementary material

11892_2017_941_MOESM1_ESM.docx (25 kb)
ESM 1 (DOCX 24 kb)
11892_2017_941_MOESM2_ESM.docx (36 kb)
ESM 2 (DOCX 36 kb)

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Santos Villafaina
    • 1
  • Daniel Collado-Mateo
    • 1
  • Juan Pedro Fuentes
    • 1
  • Eugenio Merellano-Navarro
    • 2
  • Narcis Gusi
    • 1
  1. 1.Faculty of Sport ScienceUniversity of ExtremaduraCaceresSpain
  2. 2.Facultad de EducaciónUniversidad Autónoma de ChileTalcaChile

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