Epidemiology of Head and Neck Squamous Cell Carcinomas: Impact on Staging and Prevention Strategies

  • Jessica D. McDermott
  • Daniel W. BowlesEmail author
Head and Neck Cancer (CP Rodriguez, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Head and Neck Cancer

Opinion statement

The epidemiology of head and neck squamous cell carcinoma (HNSCC) has shifted dramatically over the last 50 years, as smoking-related HNSCCs decrease in incidence while human papillomavirus (HPV)-related cancers rise. The shift in HNSCC risk factors has changed patient demographics, the distribution of affected anatomical subsites, and prognosis of this illness. As such, the medical community has responded by devising novel staging systems and prevention strategies. The medical community will require continued vigilance in reducing HNSCC traditional risks factors for HNSCC, such as cigarette use, and emerging risk like HPV infection.


Head and neck squamous cell carcinoma Human papillomavirus Epidemiology Head and neck cancer 


Compliance With Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. 1.Division of Medical Oncology, Department of MedicineUniversity of Colorado School of MedicineAuroraUSA
  2. 2.Hematology/Oncology SectionRocky Mountain Regional Veterans Affairs Medical CenterAuroraUSA

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