Abstract
Background
The Bacille-Calmette-Guérin (BCG) vaccine is used in Mycobacterium tuberculosis prophylaxis in at risk tuberculin-negative healthcare workers. Its use is contraindicated however in individuals with HIV infection.
Aims
We herein highlight the case of a healthcare worker who developed a localised reaction at a BCG vaccination site and who was subsequently found to be HIV positive.
Conclusion
This case emphasises the importance of eliciting risk factors for immunocompromise in individuals for whom BCG vaccination is being considered.
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References
Colditz GA, Brewer TF, Berkey CS et al (1994) Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature. JAMA 271(9):698–702
Sepkowitz KA (1994) Tuberculosis and the health care worker: a historical perspective. Ann Intern Med 120:71–79
Fitzgerald JM (2000) Management of adverse reactions to Bacille Calmette-Guérin vaccine. Clin Infect Dis 31(Suppl 3):S75–S76
Bolger T, O’Connell M, Butler K (2004) Complications associated with the Bacille Calmette Guerin vaccination in Ireland. Abstracts of Irish Paediatric Association. IJMS 173(4):e5
Whalen C, Horsburgh CR, Hom D et al (1995) Accelerated course of human immunodeficiency virus infection after tuberculosis. Am J Respir Crit Care Med 151(1):129–135
Kizza HM, Rodriguez B, Quinones-Mateu M et al (2005) Persistent replication of human immunodeficiency virus type 1 despite treatment of pulmonary tuberculosis in dually infected subjects. Clin Diagn Lab Immunol 12(11):1298–1304
National Collaborating Centre for Chronic Conditions (2006) Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control. Royal College of Physicians, London
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Garvey, J.F., Gueret, P. & McDonnell, T.J. Adverse reaction to Bacille-Calmette-Guérin vaccine in a HIV positive healthcare worker. Ir J Med Sci 176, 237–238 (2007). https://doi.org/10.1007/s11845-007-0072-4
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DOI: https://doi.org/10.1007/s11845-007-0072-4